000097451 001__ 97451
000097451 005__ 20230421130008.0
000097451 0247_ $$2doi$$a10.1186/s13195-020-00734-y
000097451 0248_ $$2sideral$$a121698
000097451 037__ $$aART-2020-121698
000097451 041__ $$aeng
000097451 100__ $$aRöhr, S.
000097451 245__ $$aEstimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study
000097451 260__ $$c2020
000097451 5060_ $$aAccess copy available to the general public$$fUnrestricted
000097451 5203_ $$aBackground: Subjective cognitive decline (SCD) is recognized as a risk stage for Alzheimer’s disease (AD) and other dementias, but its prevalence is not well known. We aimed to use uniform criteria to better estimate SCD prevalence across international cohorts.
Methods: We combined individual participant data for 16 cohorts from 15 countries (members of the COSMIC consortium) and used qualitative and quantitative (Item Response Theory/IRT) harmonization techniques to estimate SCD prevalence.
Results: The sample comprised 39, 387 cognitively unimpaired individuals above age 60. The prevalence of SCD across studies was around one quarter with both qualitative harmonization/QH (23.8%, 95%CI = 23.3–24.4%) and IRT (25.6%, 95%CI = 25.1–26.1%); however, prevalence estimates varied largely between studies (QH 6.1%, 95%CI = 5.1–7.0%, to 52.7%, 95%CI = 47.4–58.0%; IRT: 7.8%, 95%CI = 6.8–8.9%, to 52.7%, 95%CI = 47.4–58.0%). Across studies, SCD prevalence was higher in men than women, in lower levels of education, in Asian and Black African people compared to White people, in lower- and middle-income countries compared to high-income countries, and in studies conducted in later decades.
Conclusions: SCD is frequent in old age. Having a quarter of older individuals with SCD warrants further investigation of its significance, as a risk stage for AD and other dementias, and of ways to help individuals with SCD who seek medical advice. Moreover, a standardized instrument to measure SCD is needed to overcome the measurement variability currently dominant in the field.
000097451 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/Group 19$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/G03-128$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/01-0255$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/03-0815$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/06-0617$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/94-1562$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/97-1321E$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/98-0103
000097451 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000097451 590__ $$a6.982$$b2020
000097451 591__ $$aNEUROSCIENCES$$b38 / 273 = 0.139$$c2020$$dQ1$$eT1
000097451 591__ $$aCLINICAL NEUROLOGY$$b21 / 208 = 0.101$$c2020$$dQ1$$eT1
000097451 592__ $$a2.802$$b2020
000097451 593__ $$aCognitive Neuroscience$$c2020$$dQ1
000097451 593__ $$aNeurology (clinical)$$c2020$$dQ1
000097451 593__ $$aNeurology$$c2020$$dQ1
000097451 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000097451 700__ $$aPabst, A.
000097451 700__ $$aRiedel-Heller, S.G.
000097451 700__ $$aJessen, F.
000097451 700__ $$aTurana, Y.
000097451 700__ $$aHandajani, Y.S.
000097451 700__ $$aBrayne, C.
000097451 700__ $$aMatthews, F.E.
000097451 700__ $$aStephan, B.C.M.
000097451 700__ $$aLipton, R.B.
000097451 700__ $$aKatz, M.J.
000097451 700__ $$aWang, C.
000097451 700__ $$aGuerchet, M.
000097451 700__ $$aPreux, P.M.
000097451 700__ $$aMbelesso, P.
000097451 700__ $$aRitchie, K.
000097451 700__ $$aAncelin, M.L.
000097451 700__ $$aCarrière, I.
000097451 700__ $$aGuaita, A.
000097451 700__ $$aDavin, A.
000097451 700__ $$aVaccaro, R.
000097451 700__ $$aKim, K.W.
000097451 700__ $$aHan, J.W.
000097451 700__ $$aSuh, S.W.
000097451 700__ $$aShahar, S.
000097451 700__ $$aDin, N.C.
000097451 700__ $$aVanoh, D.
000097451 700__ $$avan Boxtel, M.
000097451 700__ $$aKöhler, S.
000097451 700__ $$aGanguli, M.
000097451 700__ $$aJacobsen, E.P.
000097451 700__ $$aSnitz, B.E.
000097451 700__ $$aAnstey, K.J.
000097451 700__ $$aCherbuin, N.
000097451 700__ $$aKumagai, S.
000097451 700__ $$aChen, S.
000097451 700__ $$aNarazaki, K.
000097451 700__ $$aNg, T.P.
000097451 700__ $$aGao, Q.
000097451 700__ $$aGwee, X.
000097451 700__ $$aBrodaty, H.
000097451 700__ $$aKochan, N.A.
000097451 700__ $$aTrollor, J.
000097451 700__ $$0(orcid)0000-0002-9098-655X$$aLobo, A.$$uUniversidad de Zaragoza
000097451 700__ $$0(orcid)0000-0002-3360-7015$$aLópez-Antón, R.$$uUniversidad de Zaragoza
000097451 700__ $$0(orcid)0000-0002-7297-6104$$aSantabárbara, J.$$uUniversidad de Zaragoza
000097451 700__ $$aCrawford, J.D.
000097451 700__ $$aLipnicki, D.M.
000097451 700__ $$aSachdev, P.S.
000097451 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica
000097451 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000097451 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000097451 773__ $$g12, 1 (2020), 167 [14 pp]$$pAlzheimer's research & therapy$$tAlzheimer's research & therapy$$x1758-9193
000097451 8564_ $$s761131$$uhttps://zaguan.unizar.es/record/97451/files/texto_completo.pdf$$yVersión publicada
000097451 8564_ $$s47195$$uhttps://zaguan.unizar.es/record/97451/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000097451 909CO $$ooai:zaguan.unizar.es:97451$$particulos$$pdriver
000097451 951__ $$a2023-04-21-12:41:12
000097451 980__ $$aARTICLE