Photodynamic therapy (PDT) in oncology

Juarranz, Á. ; Gilaberte, Y. (Universidad de Zaragoza) ; González, S.

Resumen: The issue is focused on Photodynamic Therapy (PDT), which is a minimally invasive therapeutic modality approved for treatment of several types of cancer and non-oncological disorders. PDT is being used in dermatology for the treatment of non-melanoma skin cancers (basal cell carcinoma, BCC, and Bowen disease, BD) and precancerous lesions (actinic keratosis, AKs), among other tumors such as: head and neck cancer and bladder and gynaecological neoplasms. PDT can also be used for cancer diagnosis by means of theragnosis (a term arising from the combination of diagnostic tests and therapy), a promising technique based on targeted fluorescent imaging and PDT. Photofrin and aminolevulinic acid and its ester derivatives are the main compounds used in clinical trials although newer photosensitizers (PSs) and delivery tools are being evaluated. This Special Issue on Cancers includes original articles on photochemical mechanisms, new PSs and delivery tools, cellular and tissue targets, cellular response (cell death or survival), vascular damage and immune response. We hope all the articles published in this Special Issue can help to improve this therapeutic cancer modality.

Idioma: Inglés

DOI: 10.3390/cancers12113341

Año: 2020

Publicado en: Cancers 12, 11 (2020), 3341 [1-5]
ISSN: 2072-6694

Factor impacto JCR: 6.639 (2020)

Categ. JCR: ONCOLOGY rank: 51 / 242 = 0.211 (2020) - Q1 - T1

Factor impacto SCIMAGO: 1.818 - Oncology (Q1) - Cancer Research (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MINECO-ISCIII-FEDER/FIS PI15-00974
Financiación: info:eu-repo/grantAgreement/ES/MINECO-ISCIII-FEDER/FIS PI18-00708

Tipo y forma: (Versión definitiva)

Área (Departamento): Área Dermatología (Dpto. Medicina, Psiqu. y Derm.)