000098180 001__ 98180
000098180 005__ 20230519145344.0
000098180 0247_ $$2doi$$a10.1111/tbed.13932
000098180 0248_ $$2sideral$$a121613
000098180 037__ $$aART-2021-121613
000098180 041__ $$aeng
000098180 100__ $$0(orcid)0000-0001-5608-781X$$aMillan, J.
000098180 245__ $$aWorldwide occurrence of haemoplasmas in wildlife: Insights into the patterns of infection, transmission, pathology and zoonotic potential
000098180 260__ $$c2021
000098180 5060_ $$aAccess copy available to the general public$$fUnrestricted
000098180 5203_ $$aHaemotropic mycoplasmas (haemoplasmas) have increasingly attracted the attention of wildlife disease researchers due to a combination of wide host range, high prevalence and genetic diversity. A systematic review identified 75 articles that investigated haemoplasma infection in wildlife by molecular methods (chiefly targeting partial 16S rRNA gene sequences), which included 131 host genera across six orders. Studies were less common in the Eastern Hemisphere (especially Africa and Asia) and more frequent in the Artiodactyla and Carnivora. Meta-analysis showed that infection prevalence did not vary by geographic region nor host order, but wild hosts showed significantly higher prevalence than captive hosts. Using a taxonomically flexible machine learning algorithm, we also found vampire bats and cervids to have greater prevalence, whereas mink, a subclade of vesper bats, and true foxes all had lower prevalence compared to the remaining sampled mammal phylogeny. Haemoplasma genotype and nucleotide diversity varied little among wild mammals but were marginally lower in primates and bats. Coinfection with more than one haemoplasma species or genotype was always confirmed when assessed. Risk factors of infection identified were sociality, age, males and high trophic levels, and both prevalence and diversity were often higher in undisturbed environments. Haemoplasmas likely use different and concurrent transmission routes and typically display enzootic dynamics when wild populations are studied longitudinally. Haemoplasma pathology is poorly known in wildlife but appears subclinical. Candidatus Mycoplasma haematohominis, which causes disease in humans, probably has it natural host in bats. Haemoplasmas can serve as a model system in ecological and evolutionary studies, and future research on these pathogens in wildlife must focus on increasing the geographic range and taxa of studies and elucidating pathology, transmission and zoonotic potential. To facilitate such work, we recommend using universal PCR primers or NGS protocols to detect novel haemoplasmas and other genetic markers to differentiate among species and infer cross-species transmission.
000098180 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000098180 590__ $$a4.521$$b2021
000098180 591__ $$aVETERINARY SCIENCES$$b7 / 145 = 0.048$$c2021$$dQ1$$eT1
000098180 591__ $$aINFECTIOUS DISEASES$$b44 / 96 = 0.458$$c2021$$dQ2$$eT2
000098180 594__ $$a8.6$$b2021
000098180 592__ $$a0.953$$b2021
000098180 593__ $$aVeterinary (miscellaneous)$$c2021$$dQ1
000098180 593__ $$aMedicine (miscellaneous)$$c2021$$dQ1
000098180 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/submittedVersion
000098180 700__ $$aDi Cataldo, S.
000098180 700__ $$aVolokhov, D.V.
000098180 700__ $$aBecker, D.J.
000098180 773__ $$g68, 6 (2021), 3236-3256$$pTransboundary and Emerging Diseases$$tTransboundary and Emerging Diseases$$x1865-1674
000098180 8564_ $$s656820$$uhttps://zaguan.unizar.es/record/98180/files/texto_completo.pdf$$yPreprint
000098180 8564_ $$s1113521$$uhttps://zaguan.unizar.es/record/98180/files/texto_completo.jpg?subformat=icon$$xicon$$yPreprint
000098180 909CO $$ooai:zaguan.unizar.es:98180$$particulos$$pdriver
000098180 951__ $$a2023-05-18-13:18:30
000098180 980__ $$aARTICLE