98284 20230914083306.0 doi 10.23919/CinC49843.2019.9005628 sideral 122002 ART-2019-122002 eng Varon, C. Quantification of Linear and Nonlinear Cardiorespiratory Interactions under Autonomic Nervous System Blockade 2019 Access copy available to the general public Unrestricted This paper proposes a methodology to extract both linear and nonlinear respiratory influences from the heart rate variability (HRV), by decomposing the HRV into a respiratory and a residual component. This methodology is based on least-squares support vector machines (LS-SVM) formulated for nonlinear function estimation. From this decomposition, a better estimation of the respiratory sinus arrhythmia (RSA) and the sympathovagal balance (SB) can be achieved. These estimates are first analyzed during autonomic blockade and an orthostatic maneuver, and then compared against the classical HRV and a model that considers only linear interactions. Results are evaluated using surrogate data analysis and they indicate that the classical HRV and the linear model underestimate the cardiorespiratory interactions. Moreover, the linear and nonlinear interactions appear to be mediated by different control mechanisms. These findings will allow to better assess the ANS and to improve the understanding of the interactions within the cardiorespiratory system. info:eu-repo/grantAgreement/EC/FP7/339804/EU/Biomedical Data Fusion using Tensor based Blind Source Separation/BIOTENSORS info:eu-repo/grantAgreement/ES/MINECO-FEDER/RTI2018-097723-B-I00 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.296 2019 Computer Science (miscellaneous) 2019 Cardiology and Cardiovascular Medicine 2019 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Hendrikx, D. Bolea, J. Laguna, P. Bailón, R. Universidad de Zaragoza (orcid)0000-0003-1272-0550 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 46 (2019), [4 pp] Comput. cardiol. Computing in Cardiology 2325-8861 103149 http://zaguan.unizar.es/record/98284/files/texto_completo.pdf Versión publicada 2924045 http://zaguan.unizar.es/record/98284/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:98284 articulos driver 2023-09-13-10:56:10 ARTICLE