000099331 001__ 99331
000099331 005__ 20210902121706.0
000099331 0247_ $$2doi$$a10.1039/d0fo00216j
000099331 0248_ $$2sideral$$a117795
000099331 037__ $$aART-2020-117795
000099331 041__ $$aeng
000099331 100__ $$aQuero, Javier
000099331 245__ $$aInsight into the potential application of polyphenol-rich dietary intervention in degenerative disease management
000099331 260__ $$c2020
000099331 5060_ $$aAccess copy available to the general public$$fUnrestricted
000099331 5203_ $$aIn recent times, a great number of plants have been studied in order to identify new components with nutraceutical properties, among which are polyphenols. Dietary polyphenols represent a large group of bioactive molecules widely found in the food of plant origin and they have been found able to prevent the onset and progression of degenerative diseases, and to reduce and control their symptoms. These health protective effects have been mainly related to their antioxidant and anti-inflammatory properties. However, it must be considered that the application of isolated polyphenols as nutraceuticals is quite limited due to their poor systemic distribution and relative bioavailability. The present review highlights the potential effect of dietary intervention with polyphenol-rich food and plant extracts in patients with cancer, diabetes and neurodegenerative, autoimmune, cardiovascular and ophthalmic diseases, as well as the possible molecular mechanisms of action suggested in numerous studies with animal models.
000099331 536__ $$9info:eu-repo/grantAgreement/ES/CIBERObn/CB06-03-1012$$9info:eu-repo/grantAgreement/ES/DGA/B16-R17$$9info:eu-repo/grantAgreement/ES/DGA/E104$$9info:eu-repo/grantAgreement/ES/MINECO/CTQ2016-75816-C2-1-P$$9info:eu-repo/grantAgreement/ES/MINECO/SAF2016-75441-R$$9info:eu-repo/grantAgreement/EUR/SUDOE/INTERREG/Redvalue-SOE1-PI-E0123
000099331 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000099331 590__ $$a5.396$$b2020
000099331 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b22 / 144 = 0.153$$c2020$$dQ1$$eT1
000099331 591__ $$aBIOCHEMISTRY & MOLECULAR BIOLOGY$$b76 / 297 = 0.256$$c2020$$dQ2$$eT1
000099331 592__ $$a1.145$$b2020
000099331 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000099331 593__ $$aFood Science$$c2020$$dQ1
000099331 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/acceptedVersion
000099331 700__ $$aMármol, Inés
000099331 700__ $$0(orcid)0000-0003-2457-3674$$aCerrada, Elena$$uUniversidad de Zaragoza
000099331 700__ $$0(orcid)0000-0002-3595-7668$$aRodríguez-Yoldi, María Jesús$$uUniversidad de Zaragoza
000099331 7102_ $$12010$$2760$$aUniversidad de Zaragoza$$bDpto. Química Inorgánica$$cÁrea Química Inorgánica
000099331 7102_ $$11005$$2410$$aUniversidad de Zaragoza$$bDpto. Farmacología y Fisiolog.$$cÁrea Fisiología
000099331 773__ $$g11, 4 (2020), 2805-2825$$pFOOD & FUNCTION$$tFood & function$$x2042-6496
000099331 8564_ $$s933811$$uhttps://zaguan.unizar.es/record/99331/files/texto_completo.pdf$$yPostprint
000099331 8564_ $$s1228191$$uhttps://zaguan.unizar.es/record/99331/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000099331 909CO $$ooai:zaguan.unizar.es:99331$$particulos$$pdriver
000099331 951__ $$a2021-09-02-09:17:22
000099331 980__ $$aARTICLE