99357 20210224140107.0 doi 10.1017/S0033291719002794 sideral 122895 ART-2019-122895 eng González-Ortega, I. Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis 2019 Access copy available to the general public Unrestricted Background. Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. Therefore, the main aim of this study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. Methods. The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. Results. At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (-10.215 to -0.337) and (-4.731 to -0.605) respectively). Conclusions. Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship. info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI08-01026 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI08-1161 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI08-1213 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-01977 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI11-02831 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI14-01621 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI14-01900 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-00359 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI16-01164 info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI18-00805 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 5.813 2019 PSYCHIATRY 17 / 154 = 0.11 2019 Q1 T1 PSYCHOLOGY, CLINICAL 4 / 131 = 0.031 2019 Q1 T1 PSYCHIATRY 13 / 140 = 0.093 2019 Q1 T1 PSYCHOLOGY 7 / 77 = 0.091 2019 Q1 T1 2.903 2019 Psychiatry and Mental Health 2019 Q1 Applied Psychology 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion González-Pinto, A. Alberich, S. Echeburuá, E. Bernardo, M. Cabrera, B. Amoretti, S. (orcid)0000-0002-9098-655X Lobo, A. Universidad de Zaragoza Arango, C. Corripio, I. Vieta, E. De La Serna, E. Rodriguez-Jimenez, R. Segarra, R. López-Ilundain, J.M. Sánchez-Torres, A.M. Cuesta, M.J. Zorrilla, I. López, P. Bioque, M. Mezquida, G. Barcones, F. De-La-Cámara, C. Parellada, M. Espliego, A. Alonso-Solís, A. Grasa, E.M. Varo, C. Montejo, L. Castro-Fornieles, J. Baeza, I. Dompablo, M. Torio, I. Zabala, A. Eguiluz, J.I. Moreno-Izco, L. Sanjuan, J. Guirado, R. Cáceres, I. Garnier, P. Contreras, F. Bobes, J. Al-Halabí, S. Usall, J. Butjosa, A. Sarró, S. Landin-Romero, R. Ibáñez, A. Selva, G. 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 50 (2019), 2702–2710 Psychol. med. Psychological Medicine 0033-2917 183666 http://zaguan.unizar.es/record/99357/files/texto_completo.pdf Versión publicada 3110164 http://zaguan.unizar.es/record/99357/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:99357 articulos driver 2021-02-24-12:56:14 ARTICLE