000099708 001__ 99708
000099708 005__ 20230519145501.0
000099708 0247_ $$2doi$$a10.3390/ijerph18041802
000099708 0248_ $$2sideral$$a123207
000099708 037__ $$aART-2021-123207
000099708 041__ $$aeng
000099708 100__ $$0(orcid)0000-0002-7297-6104$$aSantabárbara, J.$$uUniversidad de Zaragoza
000099708 245__ $$aA novel score for predicting alzheimer’s disease risk from late life psychopathological and health risk factors
000099708 260__ $$c2021
000099708 5060_ $$aAccess copy available to the general public$$fUnrestricted
000099708 5203_ $$aWith the increasing size of the aging population, dementia risk reduction has become a main public health concern. Dementia risk models or indices may help to identify individuals in the community at high risk to develop dementia. We have aimed to develop a novel dementia risk index focused on the late-life (65 years or more) population, that addresses risk factors for Alz-heimer’s disease (AD) easily identifiable at primary care settings. These risk factors include some shown to be associated with the risk of AD but not featured in existing indices, such as hearing loss and anxiety. Our index is also the first to account for the competing risk of death. The Zaragoza Dementia and Depression Project (ZARADEMP) Alzheimer Dementia Risk Score predicts an indi-vidual´s risk of developing AD within 5 years. The probability of late onset AD significantly in-creases in those with risk scores between 21 and 28 and, furthermore, is almost 4-fold higher for those with risk scores of 29 or higher. Our index may provide a practical instrument to identify subjects at high risk of AD and to design preventive strategies targeting the contributing risk factors.
000099708 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B15-17R$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/PI16-00896$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/Una manera de hacer Europa$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/G03-128R$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/PI-19-01874$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/01-0255$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/03-0815$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/06-0617$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/12-02254$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/16-00896$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/94-1562$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/97-1321E$$9info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/98-0103
000099708 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000099708 590__ $$a4.614$$b2021
000099708 592__ $$a0.814$$b2021
000099708 594__ $$a4.5$$b2021
000099708 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b45 / 183 = 0.246$$c2021$$dQ1$$eT1
000099708 593__ $$aPollution$$c2021$$dQ1
000099708 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b71 / 210 = 0.338$$c2021$$dQ2$$eT2
000099708 593__ $$aHealth, Toxicology and Mutagenesis$$c2021$$dQ1
000099708 591__ $$aENVIRONMENTAL SCIENCES$$b100 / 279 = 0.358$$c2021$$dQ2$$eT2
000099708 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000099708 700__ $$0(orcid)0000-0002-0519-4962$$aBueno-Notivol, J.
000099708 700__ $$aLipnicki, D.M.
000099708 700__ $$0(orcid)0000-0003-2284-7862$$ade la Cámara, C.$$uUniversidad de Zaragoza
000099708 700__ $$0(orcid)0000-0002-3360-7015$$aLópez-Antón, R.$$uUniversidad de Zaragoza
000099708 700__ $$0(orcid)0000-0002-9098-655X$$aLobo, A.$$uUniversidad de Zaragoza
000099708 700__ $$0(orcid)0000-0001-9822-6312$$aGracia-García, P.$$uUniversidad de Zaragoza
000099708 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica
000099708 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000099708 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000099708 773__ $$g18, 4 (2021), 1802 [14 pp]$$pInt. j. environ. res. public health$$tInternational journal of environmental research and public health$$x1661-7827
000099708 8564_ $$s320763$$uhttps://zaguan.unizar.es/record/99708/files/texto_completo.pdf$$yVersión publicada
000099708 8564_ $$s2759594$$uhttps://zaguan.unizar.es/record/99708/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000099708 909CO $$ooai:zaguan.unizar.es:99708$$particulos$$pdriver
000099708 951__ $$a2023-05-18-14:57:50
000099708 980__ $$aARTICLE