99708 20230519145501.0 doi 10.3390/ijerph18041802 sideral 123207 ART-2021-123207 eng Santabárbara, J. Universidad de Zaragoza (orcid)0000-0002-7297-6104 A novel score for predicting alzheimer’s disease risk from late life psychopathological and health risk factors 2021 Access copy available to the general public Unrestricted With the increasing size of the aging population, dementia risk reduction has become a main public health concern. Dementia risk models or indices may help to identify individuals in the community at high risk to develop dementia. We have aimed to develop a novel dementia risk index focused on the late-life (65 years or more) population, that addresses risk factors for Alz-heimer’s disease (AD) easily identifiable at primary care settings. These risk factors include some shown to be associated with the risk of AD but not featured in existing indices, such as hearing loss and anxiety. Our index is also the first to account for the competing risk of death. The Zaragoza Dementia and Depression Project (ZARADEMP) Alzheimer Dementia Risk Score predicts an indi-vidual´s risk of developing AD within 5 years. The probability of late onset AD significantly in-creases in those with risk scores between 21 and 28 and, furthermore, is almost 4-fold higher for those with risk scores of 29 or higher. Our index may provide a practical instrument to identify subjects at high risk of AD and to design preventive strategies targeting the contributing risk factors. info:eu-repo/grantAgreement/ES/DGA/B15-17R info:eu-repo/grantAgreement/ES/DGA-FEDER/PI16-00896 info:eu-repo/grantAgreement/ES/DGA-FEDER/Una manera de hacer Europa info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/G03-128R info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/PI-19-01874 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/01-0255 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/03-0815 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/06-0617 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/12-02254 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/16-00896 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/94-1562 info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/97-1321E info:eu-repo/grantAgreement/ES/MINECO-ISCIII/FIS/98-0103 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.614 2021 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 45 / 183 = 0.246 2021 Q1 T1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 71 / 210 = 0.338 2021 Q2 T2 ENVIRONMENTAL SCIENCES 100 / 279 = 0.358 2021 Q2 T2 0.814 2021 Pollution 2021 Q1 Health, Toxicology and Mutagenesis 2021 Q1 4.5 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Bueno-Notivol, J. (orcid)0000-0002-0519-4962 Lipnicki, D.M. de la Cámara, C. Universidad de Zaragoza (orcid)0000-0003-2284-7862 López-Antón, R. Universidad de Zaragoza (orcid)0000-0002-3360-7015 Lobo, A. Universidad de Zaragoza (orcid)0000-0002-9098-655X Gracia-García, P. Universidad de Zaragoza (orcid)0000-0001-9822-6312 4009 730 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Básica 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 1011 615 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Medic.Prevent.Salud Públ. 18, 4 (2021), 1802 [14 pp] Int. j. environ. res. public health International journal of environmental research and public health 1661-7827 320763 http://zaguan.unizar.es/record/99708/files/texto_completo.pdf Versión publicada 2759594 http://zaguan.unizar.es/record/99708/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:99708 articulos driver 2023-05-18-14:57:50 ARTICLE