000099724 001__ 99724
000099724 005__ 20230519145504.0
000099724 0247_ $$2doi$$a10.3390/ani11020381
000099724 0248_ $$2sideral$$a123223
000099724 037__ $$aART-2021-123223
000099724 041__ $$aeng
000099724 100__ $$0(orcid)0000-0003-3792-287X$$aDe las Heras, M.$$uUniversidad de Zaragoza
000099724 245__ $$aNeoplasia-associated wasting diseases with economic relevance in the sheep industry
000099724 260__ $$c2021
000099724 5060_ $$aAccess copy available to the general public$$fUnrestricted
000099724 5203_ $$aWe review three neoplastic wasting diseases affecting sheep generally recorded under common production cycles and with epidemiological and economic relevance in sheep-rearing countries: small intestinal adenocarcinoma (SIA), ovine pulmonary adenocarcinoma (OPA) and enzootic nasal adenocarcinoma (ENA). SIA is prevalent in Australia and New Zealand but present elsewhere in the world. This neoplasia is a tubular or signet-ring adenocarcinoma mainly located in the middle or distal term of the small intestine. Predisposing factors and aetiology are not known, but genetic factors or environmental carcinogens may be involved. OPA is a contagious lung cancer caused by jaagsiekte sheep retrovirus (JSRV) and has been reported in most sheep-rearing countries, resulting in significant economic losses. The disease is clinically characterized by a chronic respiratory process as a consequence of the development of lung adenocarcinoma. Diagnosis is based on the detection of JSRV in the tumour lesion by immunohistochemistry and PCR. In vivo diagnosis may be difficult, mainly in preclinical cases. ENA is a neoplasia of glands of the nasal mucosa and is associated with enzootic nasal tumour virus 1 (ENTV-1), which is similar to JSRV. ENA enzootically occurs in many countries of the world with the exception of Australia and New Zealand. The pathology associated with this neoplasia corresponds with a space occupying lesion histologically characterized as a low-grade adenocarcinoma. The combination of PCR and immunohistochemistry for diagnosis is advised.
000099724 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/Construyendo Aragón 2016–2020-A15-17R
000099724 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000099724 590__ $$a3.231$$b2021
000099724 592__ $$a0.61$$b2021
000099724 594__ $$a2.7$$b2021
000099724 591__ $$aVETERINARY SCIENCES$$b16 / 145 = 0.11$$c2021$$dQ1$$eT1
000099724 593__ $$aVeterinary (miscellaneous)$$c2021$$dQ1
000099724 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b13 / 63 = 0.206$$c2021$$dQ1$$eT1
000099724 593__ $$aAnimal Science and Zoology$$c2021$$dQ1
000099724 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000099724 700__ $$0(orcid)0000-0002-0680-9957$$aBorobia, M.$$uUniversidad de Zaragoza
000099724 700__ $$0(orcid)0000-0002-0313-5926$$aOrtín, A.$$uUniversidad de Zaragoza
000099724 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000099724 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000099724 773__ $$g11, 2 (2021), 381 [18 pp]$$pAnimals (Basel)$$tAnimals$$x2076-2615
000099724 8564_ $$s1020254$$uhttps://zaguan.unizar.es/record/99724/files/texto_completo.pdf$$yVersión publicada
000099724 8564_ $$s2583303$$uhttps://zaguan.unizar.es/record/99724/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000099724 909CO $$ooai:zaguan.unizar.es:99724$$particulos$$pdriver
000099724 951__ $$a2023-05-18-15:03:25
000099724 980__ $$aARTICLE