Resumen: Despite its undoubted potential, recent studies have began to highlight the complex processes of photothermal therapy. In this perspective, we tackle several issues that affect current research on photothermal therapy, such as the influence of other factors produced in the process, for instance reactive oxygen species or vapor nanobubbles. After focusing on several of the aspects of photothermal therapy that need further clarification, we step back and see this therapy from a wider angle in order to identify its weaknesses. Finally, we briefly summarize what we consider should be the orientation and key focus of future researches in order to establish the full potential of this rapidly advancing and promising therapy. Idioma: Inglés DOI: 10.5101/nbe.v9i2.p129-134 Año: 2017 Publicado en: Nano Biomedicine and Engineering 9, 2 (2017), 129-134 ISSN: 2150-5578 Originalmente disponible en: Texto completo de la revista