Neck circumference and clustered cardiovascular risk factors in children and adolescents: Cross-sectional study

Castro-Piñero, J. ; Delgado-Alfonso, A. ; Gracia-Marco, L. ; Gómez-Martínez, S. ; Esteban-Cornejo, I. ; Veiga, O.L. ; Marcos, A. ; Segura-Jiménez, V.

Resumen: Objective Early detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals'' health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese. Design Cross-sectional study. Setting 23 primary schools and 17 secondary schools from Spain. Participants 2198 students (1060 girls), grades 1-4 and 7-10. Measures Pubertal development, anthropometric and body composition indices, systolic and diastolic blood pressure (SBP and DBP, respectively), cardiorespiratory fitness, blood sampling triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose and inflammatory markers. Homoeostasis model assessment (HOMA-IR) and cluster of CVD risk factors were calculated. Results NC was positively correlated with all anthropometric and body composition indices. NC was negatively associated with maximum oxygen consumption (R 2 =0.231, p<0.001 for boys; R 2 =0.018, p<0.001 for girls) and positively associated with SBP, DBP, TC/HDL-c, TG, HOMA, complement factors C-3 and C-4, leptin, adiponectin and clustered CVD risk factor in both sexes (R 2 from 0.035 to 0.353, p<0.01 for boys; R 2 from 0.024 to 0.215, p<0.001 for girls). Moreover, NC was positively associated with serum C reactive protein, LDL-c and visfatin only in boys (R 2 from 0.013 to 0.107, p<0.05). Conclusion NC is a simple, low-cost and practical screening tool of excess of upper body obesity and CVD risk factors in children and adolescents. Paediatricians can easily use it as a screening tool for overweight/obesity in children and adolescents. For this purpose, sex and age-specific thresholds to classify children and adolescents as normal weight or overweight/obese are provided.

Idioma: Inglés

DOI: 10.1136/bmjopen-2017-016048

Año: 2017

Publicado en: BMJ open 7, 9 (2017), e016048[10 pp]
ISSN: 2044-6055

Factor impacto JCR: 2.413 (2017)

Categ. JCR: MEDICINE, GENERAL & INTERNAL rank: 43 / 154 = 0.279 (2017) - Q2 - T1

Factor impacto SCIMAGO: 1.372 - Medicine (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-00
Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-01
Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-02
Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-03
Financiación: info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-04

Tipo y forma: Artículo (Versión definitiva)