000064327 001__ 64327
000064327 005__ 20190709135631.0
000064327 0247_ $$2doi$$a10.1136/bmjopen-2017-016048
000064327 0248_ $$2sideral$$a103648
000064327 037__ $$aART-2017-103648
000064327 041__ $$aeng
000064327 100__ $$aCastro-Piñero, J.
000064327 245__ $$aNeck circumference and clustered cardiovascular risk factors in children and adolescents: Cross-sectional study
000064327 260__ $$c2017
000064327 5060_ $$aAccess copy available to the general public$$fUnrestricted
000064327 5203_ $$aObjective Early detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals'' health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese. Design Cross-sectional study. Setting 23 primary schools and 17 secondary schools from Spain. Participants 2198 students (1060 girls), grades 1-4 and 7-10. Measures Pubertal development, anthropometric and body composition indices, systolic and diastolic blood pressure (SBP and DBP, respectively), cardiorespiratory fitness, blood sampling triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose and inflammatory markers. Homoeostasis model assessment (HOMA-IR) and cluster of CVD risk factors were calculated. Results NC was positively correlated with all anthropometric and body composition indices. NC was negatively associated with maximum oxygen consumption (R 2 =0.231, p<0.001 for boys; R 2 =0.018, p<0.001 for girls) and positively associated with SBP, DBP, TC/HDL-c, TG, HOMA, complement factors C-3 and C-4, leptin, adiponectin and clustered CVD risk factor in both sexes (R 2 from 0.035 to 0.353, p<0.01 for boys; R 2 from 0.024 to 0.215, p<0.001 for girls). Moreover, NC was positively associated with serum C reactive protein, LDL-c and visfatin only in boys (R 2 from 0.013 to 0.107, p<0.05). Conclusion NC is a simple, low-cost and practical screening tool of excess of upper body obesity and CVD risk factors in children and adolescents. Paediatricians can easily use it as a screening tool for overweight/obesity in children and adolescents. For this purpose, sex and age-specific thresholds to classify children and adolescents as normal weight or overweight/obese are provided.
000064327 536__ $$9info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-00$$9info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-01$$9info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-02$$9info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-03$$9info:eu-repo/grantAgreement/ES/MICINN/DEP2010-21662-C04-04
000064327 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000064327 590__ $$a2.413$$b2017
000064327 591__ $$aMEDICINE, GENERAL & INTERNAL$$b43 / 154 = 0.279$$c2017$$dQ2$$eT1
000064327 592__ $$a1.372$$b2017
000064327 593__ $$aMedicine (miscellaneous)$$c2017$$dQ1
000064327 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000064327 700__ $$aDelgado-Alfonso, A.
000064327 700__ $$0(orcid)0000-0002-4020-0256$$aGracia-Marco, L.
000064327 700__ $$aGómez-Martínez, S.
000064327 700__ $$aEsteban-Cornejo, I.
000064327 700__ $$aVeiga, O.L.
000064327 700__ $$aMarcos, A.
000064327 700__ $$aSegura-Jiménez, V.
000064327 773__ $$g7, 9 (2017), e016048[10 pp]$$pBMJ Open$$tBMJ open$$x2044-6055
000064327 8564_ $$s402547$$uhttps://zaguan.unizar.es/record/64327/files/texto_completo.pdf$$yVersión publicada
000064327 8564_ $$s41096$$uhttps://zaguan.unizar.es/record/64327/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000064327 909CO $$ooai:zaguan.unizar.es:64327$$particulos$$pdriver
000064327 951__ $$a2019-07-09-12:33:15
000064327 980__ $$aARTICLE