000100768 001__ 100768 000100768 005__ 20231023123342.0 000100768 0247_ $$2doi$$a10.29007/7dsg 000100768 0248_ $$2sideral$$a122371 000100768 037__ $$aART-2019-122371 000100768 041__ $$aeng 000100768 100__ $$aQuilez, María Paz 000100768 245__ $$aCan standard implants reproduce the native kinematics of a TKA patient? 000100768 260__ $$c2019 000100768 5060_ $$aAccess copy available to the general public$$fUnrestricted 000100768 5203_ $$aTotal knee arthroplasty (TKA) is a reliable surgical procedure, yet up to a fifth of primary implant patients remains unsatisfied. Musculoskeletal modeling (MSM) has the potential to explore the relationship between implant alignment and functional outcome [3]. Consequently, implant alignment can be quantitatively optimized to restore the preTKA joint behavior and, therefore, achieve the most favorable functional outcome for the specific patient. For this reason, we developed a method to optimize the implant alignment, with the aim of restoring the native kinematics and ligament elongations of the patient before undergoing TKA. Subject-specific optimization towards ligament elongations demonstrated to accurately emulate the pre-TKA ligament behavior, in contrast to the mechanically aligned approach. However, the values of the optimized implant positions resulting from the pre-TKA kinematic optimization were extreme in some cases. The presented modelling approach is a promising starting point for allowing surgeons to evaluate the patient-specific implant alignment and restore the patientspecific biomechanics. 000100768 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000100768 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000100768 700__ $$aDelport, Hendrik Pieter 000100768 700__ $$aWirix-Speetjens, Roel 000100768 700__ $$aWesseling, Mariska 000100768 700__ $$0(orcid)0000-0002-2901-4188$$aPérez Ansón, María de los Ángeles$$uUniversidad de Zaragoza 000100768 700__ $$aJonkers, Ilse 000100768 700__ $$aVander Sloten, Jos 000100768 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est. 000100768 773__ $$g3 (2019), 311-314$$pEPiC ser. health sci.$$tEPiC series in health sciences$$x2398-5305 000100768 8564_ $$s430233$$uhttps://zaguan.unizar.es/record/100768/files/texto_completo.pdf$$yVersión publicada 000100768 8564_ $$s1742491$$uhttps://zaguan.unizar.es/record/100768/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000100768 909CO $$ooai:zaguan.unizar.es:100768$$particulos$$pdriver 000100768 951__ $$a2023-10-23-12:21:20 000100768 980__ $$aARTICLE