Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) procedure for colorectal liver metastasis

Hernandez-Alejandro, R. ; Ruffolo, L.I. ; Alikhanov, R. ; Björnsson, B. ; Torres, O.J.M. ; Serrablo, A. (Universidad de Zaragoza)

Resumen: Since first described, Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) has garnered boisterous praise and fervent criticism. Its rapid adoption and employment for a variety of indications resulted in high perioperative morbidity and mortality. However recent risk stratification, refinement of technique to reduce the impact of stage I and progression along the learning curve have resulted in improved outcomes. The first randomized trial comparing ALPPS to two stage hepatectomy (TSH) for colorectal liver metastases (CRLM) was recently published demonstrating comparable perioperative morbidity and mortality with improved resectability and survival following ALPPS. In this review, as ALPPS enters the thirteenth year since conception, the current status of this contentious two stage technique is presented and best practices for deployment in the treatment of CRLM is codified.

Idioma: Inglés

DOI: 10.1016/j.ijsu.2020.04.009

Año: 2020

Publicado en: International Journal of Surgery 82 (2020), 103-108
ISSN: 1743-9191

Factor impacto JCR: 6.071 (2020)

Categ. JCR: SURGERY rank: 15 / 212 = 0.071 (2020) - Q1 - T1

Factor impacto SCIMAGO: 1.314 - Surgery (Q1) - Medicine (miscellaneous) (Q1)

Tipo y forma: Artículo (PrePrint)

Área (Departamento): Área Cirugía (Dpto. Cirugía)