Asymmetric Fluorination Reactions promoted by Chiral Hydrogen Bonding-based Organocatalysts

Auria-Luna, F. ; Mohammadi, S. ; Divar, M. ; Gimeno, M.C. (Universidad de Zaragoza) ; Perez Herrera, R. (Universidad de Zaragoza)

Resumen: Fluorinated compounds can exhibit interesting biological properties. The importance of these species has made that the chemistry of fluorine has experienced a great development. On this review, the recent advances on asymmetric fluorination reactions promoted by chiral hydrogen bonding-based organocatalysts are discussed. Hence, examples using phosphoric acid, carboxylic acid, (thio)urea and squaramide derivatives are illustrated. The growth of this field is amazing. We have only considered pivotal works in which direct fluorination takes place using a fluorinating agent, leaving aside the reactions where a fluorine atom is incorporated from the beginning as part of other reactants. Herein, the scarce existing examples on this field of research have been compiled.

Idioma: Inglés

DOI: 10.1002/adsc.202000848

Año: 2020

Publicado en: Advanced Synthesis and Catalysis 362, 23 (2020), 5275-5300
ISSN: 1615-4150

Factor impacto JCR: 5.837 (2020)

Categ. JCR: CHEMISTRY, ORGANIC rank: 7 / 57 = 0.123 (2020) - Q1 - T1
Categ. JCR: CHEMISTRY, APPLIED rank: 11 / 74 = 0.149 (2020) - Q1 - T1

Factor impacto SCIMAGO: 1.54 - Organic Chemistry (Q1) - Catalysis (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E07-20R
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2016-75816-C2-1-P
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2017-88091-P
Financiación: info:eu-repo/grantAgreement/ES/MINECO/PID2019-104379RB-C21

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Química Inorgánica (Dpto. Química Inorgánica)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)