Resumen: Recent work shows that TRAILshort, a membrane-bound short form of TRAIL, is expressed by human cancer cells and protects them from TRAIL-induced cell death. AmAbthat selectively targets TRAILshort enhances cancer susceptibility to TRAIL and increases the efficacy of autologous CD8(+) T cells in ex vivo primary tumors. Idioma: Inglés DOI: 10.1158/1078-0432.CCR-20-2751 Año: 2020 Publicado en: CLINICAL CANCER RESEARCH 26, 21 (2020), 5546-5548 ISSN: 1078-0432 Factor impacto JCR: 12.531 (2020) Categ. JCR: ONCOLOGY rank: 18 / 242 = 0.074 (2020) - Q1 - T1 Factor impacto SCIMAGO: 5.426 - Oncology (Q1) - Cancer Research (Q1)