| TAZ-TFM-2018-664 |
Epidemiología de Blastocystis spp. en Aragón
Cristina Matovelle Ochoa
Dra. Encarnación Rubio Aranda, Dra. Mª Pilar Goñi Cepero (dir.)
Universidad de Zaragoza,
MED,
2018
Microbiología, Medicina Preventiva y Salud Pública department, Medicina Preventiva y Salud Pública area
Máster Universitario en Salud Pública
Tipo de Trabajo Académico: Trabajo Fin de Master
Notas: Blastocystis spp. it is an anaerobic protozoan that has a worldwide distribution. It is considered one of the most frequently eukaryotic parasites found in human stool samples, but it has not been until the last decades that Blastocystis spp. has been shown to be a protozoan, although it is only in recent years that it has been known the biology of this microorganism in a in more detailed way. It is described that frequency is higher in developing countries, probably indicating that the transmission is associated with lack of hygiene, exposure of animals and the consumption of contaminated food or water. There is considerable controversy about whether it is a commensal organism or a true pathogen, so it has been proposed to determine if there is a relationship between the quantification of Blastocystis spp. (> 5 parasites / field or <5 parasites / field) with the symptom that it produces, with the possible transmission routes and if these criteria has real clinical application. Therefore, a cross-sectional study was being done, based on the review of medical records, in which the variables that could be used in logistic regression models to help respond to the variables were selected using the Chi-square test that were proposed in the objective. The results showed a significant relationship with a greater number of 5 Blastocystis spp. by field with the age of the patients, presenting chest pain as a clinical symptom, having attended a medical visit, presenting type 2 diabetes mellitus as an associated comorbidity and the number of days of treatment. The rates of infection of this parasite were higher in the areas of Ejea de los Caballeros, Tarazona and Oliver in Zaragoza capital. No significant differences were found between the time distances in which the stool samples were taken comparing with the quantification of the parasite by field. This study, highlights the importance of an adequate hygiene education, which protects the population, as far as possible, the risks associated with the acquisition of parasitic diseases, also the need for future studies to determine the role played by Blastocytis spp. in digestive pathology.
Notas: Blastocystis spp. it is an anaerobic protozoan that has a worldwide distribution. It is considered one of the most frequently eukaryotic parasites found in human stool samples, but it has not been until the last decades that Blastocystis spp. has been shown to be a protozoan, although it is only in recent years that it has been known the biology of this microorganism in a in more detailed way. It is described that frequency is higher in developing countries, probably indicating that the transmission is associated with lack of hygiene, exposure of animals and the consumption of contaminated food or water. There is considerable controversy about whether it is a commensal organism or a true pathogen, so it has been proposed to determine if there is a relationship between the quantification of Blastocystis spp. (> 5 parasites / field or <5 parasites / field) with the symptom that it produces, with the possible transmission routes and if these criteria has real clinical application. Therefore, a cross-sectional study was being done, based on the review of medical records, in which the variables that could be used in logistic regression models to help respond to the variables were selected using the Chi-square test that were proposed in the objective. The results showed a significant relationship with a greater number of 5 Blastocystis spp. by field with the age of the patients, presenting chest pain as a clinical symptom, having attended a medical visit, presenting type 2 diabetes mellitus as an associated comorbidity and the number of days of treatment. The rates of infection of this parasite were higher in the areas of Ejea de los Caballeros, Tarazona and Oliver in Zaragoza capital. No significant differences were found between the time distances in which the stool samples were taken comparing with the quantification of the parasite by field. This study, highlights the importance of an adequate hygiene education, which protects the population, as far as possible, the risks associated with the acquisition of parasitic diseases, also the need for future studies to determine the role played by Blastocytis spp. in digestive pathology.
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