Influence of material and haptic design on the mechanical stability of intraocular lenses by means of finite-element modeling

Remón, L. (Universidad de Zaragoza) ; Siedlecki, D. ; Cabeza-Gil, I. ; Calvo, B. (Universidad de Zaragoza)

Resumen: Intraocular lenses (IOLs) are used in the cataract treatment for surgical replacement of the opacified crystalline lens. Before being implanted they have to pass the strict quality control to guarantee a good biomechanical stability inside the capsular bag, avoiding the rotation, and to provide a good optical quality. The goal of this study was to investigate the influence of the material and haptic design on the behavior of the IOLs under dynamic compression condition. For this purpose, the strain-stress characteristics of the hydrophobic and hydrophilic materials were estimated experimentally. Next, these data were used as the input for a finite-element model (FEM) to analyze the stability of different IOL haptic designs, according to the procedure described by the ISO standards. Finally, the simulations of the effect of IOL tilt and decentration on the optical performance were performed in an eye model using a ray-tracing software. The results suggest the major importance of the haptic design rather than the material on the postoperative behavior of an IOL. FEM appears to be a powerful tool for numerical studies of the biomechanical properties of IOLs and it allows one to help in the design phase to the manufacturers.

Idioma: Inglés

DOI: 10.1117/1.JBO.23.3.035003

Año: 2018

Publicado en: JOURNAL OF BIOMEDICAL OPTICS 23, 3 (2018), 035003 [10 pp.]
ISSN: 1083-3668

Factor impacto JCR: 2.555 (2018)

Categ. JCR: BIOCHEMICAL RESEARCH METHODS rank: 34 / 78 = 0.436 (2018) - Q2 - T2
Categ. JCR: RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING rank: 52 / 129 = 0.403 (2018) - Q2 - T2
Categ. JCR: OPTICS rank: 37 / 95 = 0.389 (2018) - Q2 - T2

Factor impacto SCIMAGO: 0.868 - Atomic and Molecular Physics, and Optics (Q1) - Electronic, Optical and Magnetic Materials (Q1) - Biomedical Engineering (Q1) - Biomaterials (Q1)

Financiación: info:eu-repo/grantAgreement/ES/MINECO/DPI2014-54981-R
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/DPI2017-84047-R
Financiación: info:eu-repo/grantAgreement/ES/UZ-IBERCAJA-CAI/CM02-7
Financiación: info:eu-repo/grantAgreement/ES/UZ/ICTS NANBIOSIS-U13 Unit-CIBER-BBN

Tipo y forma: Article (Published version)

Área (Departamento): Área Óptica (Dpto. Física Aplicada)
Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)