Methodology to calibrate the dissection properties of aorta layers from two sets of experimental measurements

Ríos Ruiz I. (Universidad de Zaragoza) ; Cilla Hernández, M. ; Martínez Barca, M.A. (Universidad de Zaragoza) ; Peña Baquedano E. (Universidad de Zaragoza)

Resumen: Aortic dissection is a prevalent cardiovascular pathology that can have a fatal outcome. However, the mechanisms that trigger this disease and the mechanics of its progression are not fully understood. Computational models can help understand these issues, but they need a proper characterisation of the tissues. Therefore, we propose a methodology to obtain the dissection parameters of all layers in aortic tissue via the computational modelling of two different delamination tests: the peel and mixed tests. Both experimental tests have been performed in specimens of porcine aorta, where the intima-media and media-adventitia interfaces, as well as the medial layer, were dissected. These two tests have been modelled using a cohesive zone formulation for the separating interface and a hyperelastic anisotropic material model via an implicit static analysis. The dissection properties of each interface have been calibrated by reproducing the force-displacement curves obtained in the experimental tests. The values of peak and mean force of the experiments were fitted with an error below 10%. With this methodology, we intend to contribute to the development of reliable numerical tools for simulating aortic dissection and aortic aneurysm rupture. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Idioma: Inglés

DOI: 10.3390/math9141593

Año: 2021

Publicado en: Mathematics 9, 14 (2021), 1593 [11 pp]
ISSN: 2227-7390

Factor impacto JCR: 2.592 (2021)

Categ. JCR: MATHEMATICS rank: 21 / 333 = 0.063 (2021) - Q1 - T1

Factor impacto CITESCORE: 2.9 - Engineering (Q2) - Mathematics (Q2) - Computer Science (Q3)

Factor impacto SCIMAGO: 0.538 - Computer Science (miscellaneous) (Q2) - Engineering (miscellaneous) (Q2)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Mec.Med.Cont. y Teor.Est. (Dpto. Ingeniería Mecánica)