Early Nutrition and Later Excess Adiposity during Childhood: A Narrative Review

Iglesia Altaba, Iris ; Larqué, Elvira ; Mesa, María Dolores ; Blanco-Carnero, José Eliseo ; Gomez-Llorente, Carolina ; Rodríguez-Martínez, Gerardo (Universidad de Zaragoza) ; Moreno, Luis A. (Universidad de Zaragoza)

Resumen: Background: Studies on childhood obesity mainly focus on the genetic component and on the lifestyle that may be associated with the development of obesity. However, the study of perinatal factors in their programming effect toward future obesity in children or adults is somewhat more recent, and there are still mechanisms to be disentangled. Summary: In this narrative review, a comprehensive route based on the influence of some early factors in life in the contribution to later obesity development is presented. Maternal pre-pregnancy BMI and gestational weight gain have been pointed out as independent determinants of infant later adiposity. Lifestyle interventions could have an impact on pregnant mothers through epigenetic mechanisms capable of redirecting the genetic expression of their children toward a future healthy weight and body composition and dietary-related microbiome modifications in mothers and newborns might also be related. After birth, infant feeding during the first months of life is directly associated with its body composition and nutritional status. From this point of view, all the expert committees in the world are committed to promote exclusive breastfeeding up to 6 months of age and to continue at least until the first year of life together with complementary feeding based on healthy dietary patterns such as Mediterranean Diet.

Idioma: Inglés

DOI: 10.1159/000520811

Año: 2022

Publicado en: HORMONE RESEARCH IN PAEDIATRICS 95, 2 (2022), 112-119
ISSN: 1663-2818

Factor impacto JCR: 3.2 (2022)

Categ. JCR: PEDIATRICS rank: 34 / 130 = 0.262 (2022) - Q2 - T1
Categ. JCR: ENDOCRINOLOGY & METABOLISM rank: 89 / 144 = 0.618 (2022) - Q3 - T2

Factor impacto CITESCORE: 5.6 - Medicine (Q1) - Biochemistry, Genetics and Molecular Biology (Q2)

Factor impacto SCIMAGO: 0.836 - Pediatrics, Perinatology and Child Health (Q1) - Endocrinology (Q2) - Endocrinology, Diabetes and Metabolism (Q2)

Financiación: info:eu-repo/grantAgreement/ES/RETICS-ISCIII-ERDF/RD16-0022

Tipo y forma: Artículo (PostPrint)

Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)
Área (Departamento): Área Pediatría (Dpto. Microb.Ped.Radio.Sal.Pú.)