SK channels contribution to ventricular electrophysiology in heart failure patients

Pérez Martínez, A. (Universidad de Zaragoza) ; García Mendívil, L. (Universidad de Zaragoza) ; López Yus, M. ; Mancebón Sierra, F. J. ; Vaca Núñez, A.S. ; Ballester Cuenca, C. (Universidad de Zaragoza) ; Pérez Zabalza, M. ; Kohler, R. ; Pueyo, E. (Universidad de Zaragoza) ; Oliván Viguera, A.

Resumen: Heart failure (HF) is characterized by deterioration of the electrical and contractile function of the heart due to structural and functional remodelling, leading to development of arrhythmias and increased sudden cardiac death risk. SK channels are a type of calcium-activated potassium channels that do not play a relevant role in normal ventricular electrophysiology. However, it has been hypothesized that these channels become more relevant in pathologies such as HF. Nontheless, their role in human ventricular electrophysiology is not fully characterized.

Idioma: Inglés

DOI: 10.1093/cvr/cvac066.022

Año: 2022

Publicado en: Cardiovascular research 118, Supp. 1 (2022), [1 pp.]
ISSN: 0008-6363

Factor impacto JCR: 10.9 (2022)

Categ. JCR: CARDIAC & CARDIOVASCULAR SYSTEMS rank: 12 / 143 = 0.084 (2022) - Q1 - T1

Factor impacto CITESCORE: 18.3 - Medicine (Q1) - Biochemistry, Genetics and Molecular Biology (Q1)

Factor impacto SCIMAGO: 2.481 - Cardiology and Cardiovascular Medicine (Q1) - Physiology (medical) (Q1) - Physiology (Q1)

Tipo y forma: Article (Published version)

Área (Departamento): Área Cirugía (Dpto. Cirugía)
Área (Departamento): Área Teoría Señal y Comunicac. (Dpto. Ingeniería Electrón.Com.)