Clinical leishmaniosis in a domestic ferret (Mustela putorius furo) treated with miltefosine plus allopurinol: Serological and clinical follow-up

Giner J. ; Villanueva Saz S. (Universidad de Zaragoza) ; Alcover M.M. ; Riera C. ; Fisa R. ; Verde Arribas M. (Universidad de Zaragoza) ; Fernández Casasnovas A. (Universidad de Zaragoza) ; Yzuel A.

Resumen: The published information on the treatment of mustelid leishmaniosis is extremely scarce because there are only two case reports available. In one case, a domestic ferret (Mustela putorius furo) was treated with a combination of meglumine antimoniate plus allopurinol and, in the other case, a therapeutic regimen with allopurinol was administrated to a Eurasian otter (Lutra lutra). This article describes for the first time a combined therapeutic protocol with miltefosine (2 mg/kg once a day during 28 days per os), and allopurinol (10 mg/kg twice a day PO sine die) in a domestic ferret with splenomegaly, lymphadenomegaly and a facial pyogranulomatous dermatitis, with a moderate level of antibodies to Leishmania infantum. © 2021 Elsevier B.V.

Idioma: Inglés

DOI: 10.1016/j.vprsr.2021.100607

Año: 2021

Publicado en: Veterinary Parasitology: Regional Studies and Reports 25 (2021), 100607 [4 pp]
ISSN: 2405-9390

Factor impacto CITESCORE: 2.6 - Veterinary (Q2) - Immunology and Microbiology (Q3)

Factor impacto SCIMAGO: 0.52 - Veterinary (miscellaneous) (Q1) - Parasitology (Q1)

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Medicina y Cirugía Animal (Dpto. Patología Animal)