Resumen: In contrast to strong evidence-based clinical recommendations for lipid-lowering treatment, there is no analogous definitive diagnostic definition of hypercholesterolemia and its various subtypes. For many clinicians, guideline indications for hypolipidemic treatment can become broadly conflated with hypercholesterolemia in a non-specific sense. In this statement, we propose a unified definition and mechanism-based classification of hypercholesterolemia, which in turn should help to stratify patients and guide efficient diagnosis without interfering with the current strategies of ASCVD risk reduction. Idioma: Inglés DOI: 10.1016/j.jacl.2022.09.006 Año: 2022 Publicado en: Journal of Clinical Lipidology 16, 6 (2022), 813-821 ISSN: 1933-2874 Factor impacto JCR: 4.4 (2022) Categ. JCR: PHARMACOLOGY & PHARMACY rank: 81 / 278 = 0.291 (2022) - Q2 - T1 Factor impacto CITESCORE: 7.4 - Nursing (Q1) - Medicine (Q1)