A mechanism-based operational definition and classification of hypercholesterolemia

Civeira, Fernando (Universidad de Zaragoza) ; Arca, Marcello ; Cenarro, Ana ; Hegele, Robert A.

Resumen: In contrast to strong evidence-based clinical recommendations for lipid-lowering treatment, there is no analogous definitive diagnostic definition of hypercholesterolemia and its various subtypes. For many clinicians, guideline indications for hypolipidemic treatment can become broadly conflated with hypercholesterolemia in a non-specific sense. In this statement, we propose a unified definition and mechanism-based classification of hypercholesterolemia, which in turn should help to stratify patients and guide efficient diagnosis without interfering with the current strategies of ASCVD risk reduction.

Idioma: Inglés

DOI: 10.1016/j.jacl.2022.09.006

Año: 2022

Publicado en: Journal of Clinical Lipidology 16, 6 (2022), 813-821
ISSN: 1933-2874

Factor impacto JCR: 4.4 (2022)

Categ. JCR: PHARMACOLOGY & PHARMACY rank: 81 / 278 = 0.291 (2022) - Q2 - T1

Factor impacto CITESCORE: 7.4 - Nursing (Q1) - Medicine (Q1)

Factor impacto SCIMAGO: 1.256 - Cardiology and Cardiovascular Medicine (Q1) - Nutrition and Dietetics (Q1) - Internal Medicine (Q1) - Endocrinology, Diabetes and Metabolism (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/B14-7R
Financiación: info:eu-repo/grantAgreement/ES/ISCIII-MINECO/PI19-00694

Tipo y forma: Article (Published version)

Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)