A cross-sectional study examining the parametric thyroid feedback quantile index and its relationship with metabolic and cardiovascular diseases

Alonso-Ventura, Vanesa (Universidad de Zaragoza) ; Civeira, Fernando (Universidad de Zaragoza) ; Alvarado-Rosas, Almendra ; Lou-Bonafonte, Jose Manuel (Universidad de Zaragoza) ; Calmarza, Pilar ; Moreno-Franco, Belen (Universidad de Zaragoza) ; Andres-Otero, María Jesús ; Calvo-Gracia, Fernando (Universidad de Zaragoza) ; Diego-García, Patricia de ; Laclaustra, Martín (Universidad de Zaragoza)

Resumen: The usual inverse correlation between thyrotropin (TSH) and thyroid hormone disappears in syndromes of central resistance to thyroid hormone, where both are high. TSH and thyroid hormone are also simultaneously high when there is an elevation of the set point of the thyroid regulation axis. This can be estimated with indices, such as the Parametric Thyroid Feedback Quantile-based Index (PTFQI), which was designed for the general population. The PTFQI is positively associated with diabetes prevalence, but association with other pathologies has not been yet explored. The aim of this project was to explore the potential relationship of the PTFQI with metabolic and cardiovascular disease in a sample of ambulatory adult patients from Spain.

Idioma: Inglés

DOI: 10.1089/thy.2022.0025

Año: 2022

Publicado en: THYROID 32, 12 (2022), [12 pp.]
ISSN: 1050-7256

Factor impacto JCR: 6.6 (2022)

Categ. JCR: ENDOCRINOLOGY & METABOLISM rank: 24 / 144 = 0.167 (2022) - Q1 - T1

Factor impacto CITESCORE: 11.8 - Medicine (Q1) - Biochemistry, Genetics and Molecular Biology (Q1)

Factor impacto SCIMAGO: 1.609 - Endocrinology (Q1) - Medicine (miscellaneous) (Q1) - Endocrinology, Diabetes and Metabolism (Q1)

Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI19-00020

Tipo y forma: Article (Published version)

Área (Departamento): Área Fisiología (Dpto. Farmac.Fisiol.y Med.L.F.)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
Área (Departamento): Área Medic.Prevent.Salud Públ. (Dpto. Microb.Ped.Radio.Sal.Pú.)