Management of iron-deficiency anemia following acute gastrointestinal hemorrhage: A narrative analysis and review
Lanas, Angel (Universidad de Zaragoza) ; Andrews, Jane M ; Lau, James ; Toruner, Murat ; Bromley, Susan E ; Gralnek, Ian M
Resumen: Many patients experiencing acute gastrointestinal bleeding (GIB) require iron supplemen-tation to treat subsequent iron deficiency (ID) or iron-deficiency anemia (IDA). Guidelinesregarding management of these patients are lacking. We aimed to identify areas of unmetneed in patients with ID/IDA following acute GIB in terms of patient management andphysician guidance. We formed an international working group of gastroenterologists toconduct a narrative review based on PubMed and EMBASE database searches (fromJanuary 2000 to February 2021), integrated with observations from our own clinical expe-rience. Published data on this subject are limited and disparate, and those relating topost-discharge outcomes, such as persistent anemia and re-hospitalization, are particularlylacking. Often, there is no post-discharge follow-up of these patients by a gastroenterolo-gist. Acute GIB-related ID/IDA, however, is a prevalent condition both at the time of hos-pital admission and at hospital discharge and is likely underdiagnosed and undertreated.Despite limited data, there appears to be notable variation in the prescribing of intravenous(IV)/oral iron regimens. There is also some evidence suggesting that, compared with oraliron, IV iron may restore iron levels faster following acute GIB, have a better tolerabilityprofile, and be more beneficial in terms of quality of life. Gaps in patient care exist inthe management of acute GIB-related ID/IDA, yet further data from largepopulation-based studies are needed to confirm this. We advocate the formulation ofevidence-based guidance on the use of iron therapies in these patients, aiding a more stan-dardized best-practice approach to patient care.
Idioma: Inglés
DOI: 10.1111/jgh.16033
Año: 2023
Publicado en: Journal of Gastroenterology and Hepatology (Australia) 38, 1 (2023), 23-33
ISSN: 0815-9319
Factor impacto JCR: 3.7 (2023)
Categ. JCR: GASTROENTEROLOGY & HEPATOLOGY rank: 40 / 143 = 0.28 (2023) - Q2 - T1
Factor impacto CITESCORE: 7.9 - Hepatology (Q2) - Gastroenterology (Q1)
Factor impacto SCIMAGO: 1.179 - Gastroenterology (Q1) - Hepatology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2024-11-22-11:58:13)
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Idioma: Inglés
DOI: 10.1111/jgh.16033
Año: 2023
Publicado en: Journal of Gastroenterology and Hepatology (Australia) 38, 1 (2023), 23-33
ISSN: 0815-9319
Factor impacto JCR: 3.7 (2023)
Categ. JCR: GASTROENTEROLOGY & HEPATOLOGY rank: 40 / 143 = 0.28 (2023) - Q2 - T1
Factor impacto CITESCORE: 7.9 - Hepatology (Q2) - Gastroenterology (Q1)
Factor impacto SCIMAGO: 1.179 - Gastroenterology (Q1) - Hepatology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2024-11-22-11:58:13)
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Record created 2022-12-21, last modified 2024-11-25