The migration of NIAS from ethylene-vinyl acetate corks and their identification using gas chromatography mass spectrometry and liquid chromatography ion mobility quadrupole time-of-flight mass spectrometry

Vera, Paula (Universidad de Zaragoza) ; Canellas, Elena (Universidad de Zaragoza) ; Nerín, Cristina (Universidad de Zaragoza) ; Dreolin, Nicola ; Goshawk, Jeff

Resumen: An exhaustive migration study of eight corks, made of ethylene–vinyl acetate, was carried out to identify any non-volatile and volatile compounds using an untargeted approach. The challenge associated with the structural elucidation of unknowns was undertaken using both ultra-high-performance liquid chromatography coupled to an ion-mobility separation quadrupole-time of flight mass spectrometer and gas chromatography mass spectrometry. A total of fifty compounds were observed to migrate from the corks, and among these additives such as antioxidants (Butyl 4-hydroxybenzoate, Irganox 1010, Irganox 1075, Irgafos 168 and BHT) or lubricants (EBO and octadecanamide, N,N'-1,2-ethanediylbis-) were identified. A high proportion (84%) of the detected compounds was non-intentionally added substances (NIAS), and included several cyclic oligomers with different chain sequences. NIAS, such as 2,6-bis(1,1-dimethylethyl)-4-ethyl and 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione, break-down products, including hexa-, hepta- and nonadecanamide, N,N'-1,2-ethanediylbis-, and oxidation products were also identified. One cork was found to be unsuitable for use as a food contact material.

Idioma: Inglés

DOI: 10.1016/j.foodchem.2021.130592

Año: 2022

Publicado en: Food Chemistry 366 (2022), 130592 [10 pp.]
ISSN: 0308-8146

Factor impacto JCR: 8.8 (2022)

Categ. JCR: CHEMISTRY, APPLIED rank: 5 / 72 = 0.069 (2022) - Q1 - T1
Categ. JCR: NUTRITION & DIETETICS rank: 5 / 87 = 0.057 (2022) - Q1 - T1
Categ. JCR: FOOD SCIENCE & TECHNOLOGY rank: 9 / 142 = 0.063 (2022) - Q1 - T1

Factor impacto CITESCORE: 14.9 - Agricultural and Biological Sciences (Q1) - Chemistry (Q1) - Medicine (Q1)

Factor impacto SCIMAGO: 1.624 - Analytical Chemistry (Q1) - Medicine (miscellaneous) (Q1) - Food Science (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA-FEDER/T53-20R
Financiación: info:eu-repo/grantAgreement/ES/MICINN/RTI2018-097805-B-I00

Tipo y forma: Article (Published version)

Área (Departamento): Área Química Analítica (Dpto. Química Analítica)