000121177 001__ 121177 000121177 005__ 20240319081015.0 000121177 0247_ $$2doi$$a10.3390/jcm11020421 000121177 0248_ $$2sideral$$a131829 000121177 037__ $$aART-2022-131829 000121177 041__ $$aeng 000121177 100__ $$aZabana, Yamile 000121177 245__ $$aNationwide COVID-19-EII Study: Incidence, Environmental Risk Factors and Long-Term Follow-Up of Patients with Inflammatory Bowel Disease and COVID-19 of the ENEIDA Registry 000121177 260__ $$c2022 000121177 5060_ $$aAccess copy available to the general public$$fUnrestricted 000121177 5203_ $$aWe aim to describe the incidence and source of contagion of COVID-19 in patients with IBD, as well as the risk factors for a severe course and long-term sequelae. This is a prospective observational study of IBD and COVID-19 included in the ENEIDA registry (53,682 from 73 centres) between March–July 2020 followed-up for 12 months. Results were compared with data of the general population (National Centre of Epidemiology and Catalonia). A total of 482 patients with COVID-19 were identified. Twenty-eight percent were infected in the work environment, and 48% were infected by intrafamilial transmission, despite having good adherence to lockdown. Thirty-five percent required hospitalization, 7.9% had severe COVID-19 and 3.7% died. Similar data were reported in the general population (hospitalisation 19.5%, ICU 2.1% and mortality 4.6%). Factors related to death and severe COVID-19 were being aged ≥ 60 years (OR 7.1, 95% CI: 1.8–27 and 4.5, 95% CI: 1.3–15.9), while having ≥2 comorbidities increased mortality (OR 3.9, 95% CI: 1.3–11.6). None of the drugs for IBD were related to severe COVID-19. Immunosuppression was definitively stopped in 1% of patients at 12 months. The prognosis of COVID-19 in IBD, even in immunosuppressed patients, is similar to that in the general population. Thus, there is no need for more strict protection measures in IBD. 000121177 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/COV20-00227 000121177 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000121177 590__ $$a3.9$$b2022 000121177 592__ $$a0.935$$b2022 000121177 591__ $$aMEDICINE, GENERAL & INTERNAL$$b58 / 169 = 0.343$$c2022$$dQ2$$eT2 000121177 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1 000121177 594__ $$a5.4$$b2022 000121177 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000121177 700__ $$aMarín-Jiménez, Ignacio 000121177 700__ $$aRodríguez-Lago, Iago 000121177 700__ $$aVera, Isabel 000121177 700__ $$aMartín-Arranz, María Dolores 000121177 700__ $$aGuerra, Iván 000121177 700__ $$aGisbert, Javier P. 000121177 700__ $$aMesonero, Francisco 000121177 700__ $$aBenítez, Olga 000121177 700__ $$aTaxonera, Carlos 000121177 700__ $$aPonferrada-Díaz, Ángel 000121177 700__ $$aPiqueras, Marta 000121177 700__ $$aLucendo, Alfredo J. 000121177 700__ $$aCaballol, Berta 000121177 700__ $$aMañosa, Míriam 000121177 700__ $$aMartínez-Montiel, Pilar 000121177 700__ $$aBosca-Watts, Maia 000121177 700__ $$aGordillo, Jordi 000121177 700__ $$aBujanda, Luis 000121177 700__ $$aManceñido, Noemí 000121177 700__ $$aMartínez-Pérez, Teresa 000121177 700__ $$aLópez, Alicia 000121177 700__ $$aRodríguez-Gutiérrez, Cristina 000121177 700__ $$0(orcid)0000-0003-3970-5457$$aGarcía-López, Santiago$$uUniversidad de Zaragoza 000121177 700__ $$aVega, Pablo 000121177 700__ $$aRivero, Montserrat 000121177 700__ $$aMelcarne, Luigi 000121177 700__ $$aCalvo, Maria 000121177 700__ $$aIborra, Marisa 000121177 700__ $$aBarreiro de-Acosta, Manuel 000121177 700__ $$aSicilia, Beatriz 000121177 700__ $$aBarrio, Jesús 000121177 700__ $$aPérez, José Lázaro 000121177 700__ $$aBusquets, David 000121177 700__ $$aPérez-Martínez, Isabel 000121177 700__ $$aNavarro-Llavat, Mercè 000121177 700__ $$aHernández, Vicent 000121177 700__ $$aArgüelles-Arias, Federico 000121177 700__ $$aRamírez Esteso, Fernando 000121177 700__ $$aMeijide, Susana 000121177 700__ $$aRamos, Laura 000121177 700__ $$aGomollón, Fernando 000121177 700__ $$aMuñoz, Fernando 000121177 700__ $$aSuris, Gerard 000121177 700__ $$ade Zarate, Jone Ortiz 000121177 700__ $$aHuguet, José María 000121177 700__ $$aLlaó, Jordina 000121177 700__ $$aGarcía-Sepulcre, Mariana Fe 000121177 700__ $$aSierra, Mónica 000121177 700__ $$aDurà, Miguel 000121177 700__ $$aEstrecha, Sandra 000121177 700__ $$aFuentes Coronel, Ana 000121177 700__ $$aHinojosa, Esther 000121177 700__ $$aOlivan, Lorenzo 000121177 700__ $$aIglesias, Eva 000121177 700__ $$aGutiérrez, Ana 000121177 700__ $$aVarela, Pilar 000121177 700__ $$aRull, Núria 000121177 700__ $$aGilabert, Pau 000121177 700__ $$aHernández-Camba, Alejandro 000121177 700__ $$aBrotons, Alicia 000121177 700__ $$aGinard, Daniel 000121177 700__ $$aSesé, Eva 000121177 700__ $$aCarpio, Daniel 000121177 700__ $$aAceituno, Montserrat 000121177 700__ $$aCabriada, José Luis 000121177 700__ $$aGonzález-Lama, Yago 000121177 700__ $$aJiménez, Laura 000121177 700__ $$aChaparro, María 000121177 700__ $$aLópez-San Román, Antonio 000121177 700__ $$aAlba, Cristina 000121177 700__ $$aPlaza-Santos, Rocío 000121177 700__ $$aMena, Raquel 000121177 700__ $$aTamarit-Sebastián, Sonsoles 000121177 700__ $$aRicart, Elena 000121177 700__ $$aCalafat, Margalida 000121177 700__ $$aOlivares, Sonsoles 000121177 700__ $$aNavarro, Pablo 000121177 700__ $$aBertoletti, Federico 000121177 700__ $$aAlonso-Galán, Horacio 000121177 700__ $$aPajares, Ramón 000121177 700__ $$aOlcina, Pablo 000121177 700__ $$aManzano, Pamela 000121177 700__ $$aDomènech, Eugeni 000121177 700__ $$aEsteve, Maria 000121177 700__ $$a 000121177 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000121177 773__ $$g11, 2 (2022), 421 [20 pp.]$$pJ. clin.med.$$tJournal of Clinical Medicine$$x2077-0383 000121177 8564_ $$s1088178$$uhttps://zaguan.unizar.es/record/121177/files/texto_completo.pdf$$yVersión publicada 000121177 8564_ $$s3020822$$uhttps://zaguan.unizar.es/record/121177/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000121177 909CO $$ooai:zaguan.unizar.es:121177$$particulos$$pdriver 000121177 951__ $$a2024-03-18-15:35:12 000121177 980__ $$aARTICLE