Obstetric and perinatal outcomes of pregnancies with COVID 19: a systematic review and meta-analysis
Pérez-López, Faustino R. ; Savirón-Cornudella, Ricardo (Universidad de Zaragoza) ; Chedraui, Peter ; López-Baena, María T. ; Pérez-Roncero, Gonzalo (Universidad de Zaragoza) ; Sanz-Arenal, Ana ; Narváez-Salazar, Marta ; Dieste-Pérez, Peña ; Tajada, Mauricio (Universidad de Zaragoza)
Resumen: Objective.
This meta-analysis aimed at comparing obstetric and perinatal outcomes in laboratory-tested pregnant women for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection before delivering.
Method.
We performed a comprehensive systematic review of electronic databases for studies reporting pregnant women with and without SARS-CoV-2 infection, as determined by polymerase chain reaction (PCR) before delivery, during the pandemic period published up to June 25, 2021. Results are reported as mean difference (MD) or odds ratio (OR) and their 95% confidence interval (CI).
Results.
Seventeen observational studies with low to moderate risk of bias, reported on 2,769 pregnant women with a positive SARS-CoV-2 PCR test and 13,807 with a negative test. Pregnant women with a positive PCR test delivered at an earlier gestational age (MD −0.19; 95% CI −0.36 to −0.02 weeks), smoked less (OR 0.75; 95% CI 0.61–0.94) and were associated with higher odds for preeclampsia (OR 1.30; 95% CI 1.09–1.54), NICU admissions (OR 2.37; 95% CI 1.18–4.76), stillbirths (OR 2.70; 95% CI, 1.38–5.29), and perinatal mortality (OR 3.23; 95% CI 1.23–8.52). There were no significant differences between positive and negative tested women in terms of nulliparity, multiple pregnancies, gestational diabetes, route of delivery, labor induction, preterm birth, infant birth weight, 5 min Apgar scores < 7, small-for-gestational-age infants and fetal malformations. Eleven studies included neonatal PCR SARS-CoV-2 testing which was performed on 129 infants, of which 20 were positive.
Conclusion.
Positive SARS-CoV-2 tested pregnant women had higher odds for preeclampsia/hypertensive disorders of pregnancy, NICU admissions, stillbirths and perinatal mortality.
Idioma: Inglés
DOI: 10.1080/14767058.2022.2051008
Año: 2022
Publicado en: Journal of Maternal-Fetal and Neonatal Medicine 35, 25 (2022), 9742-9758
ISSN: 1476-7058
Factor impacto JCR: 1.8 (2022)
Categ. JCR: OBSTETRICS & GYNECOLOGY rank: 67 / 85 = 0.788 (2022) - Q4 - T3
Factor impacto CITESCORE: 3.9 - Medicine (Q2)
Factor impacto SCIMAGO: 0.664 - Pediatrics, Perinatology and Child Health (Q2) - Obstetrics and Gynecology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)
Área (Departamento): Area Anatom.Embriol.Humana (Dpto. Anatom.Histolog.Humanas)
Área (Departamento): Área Obstetricia y Ginecología (Dpto. Cirugía)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material.
Exportado de SIDERAL (2024-03-18-16:05:12)
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This meta-analysis aimed at comparing obstetric and perinatal outcomes in laboratory-tested pregnant women for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection before delivering.
Method.
We performed a comprehensive systematic review of electronic databases for studies reporting pregnant women with and without SARS-CoV-2 infection, as determined by polymerase chain reaction (PCR) before delivery, during the pandemic period published up to June 25, 2021. Results are reported as mean difference (MD) or odds ratio (OR) and their 95% confidence interval (CI).
Results.
Seventeen observational studies with low to moderate risk of bias, reported on 2,769 pregnant women with a positive SARS-CoV-2 PCR test and 13,807 with a negative test. Pregnant women with a positive PCR test delivered at an earlier gestational age (MD −0.19; 95% CI −0.36 to −0.02 weeks), smoked less (OR 0.75; 95% CI 0.61–0.94) and were associated with higher odds for preeclampsia (OR 1.30; 95% CI 1.09–1.54), NICU admissions (OR 2.37; 95% CI 1.18–4.76), stillbirths (OR 2.70; 95% CI, 1.38–5.29), and perinatal mortality (OR 3.23; 95% CI 1.23–8.52). There were no significant differences between positive and negative tested women in terms of nulliparity, multiple pregnancies, gestational diabetes, route of delivery, labor induction, preterm birth, infant birth weight, 5 min Apgar scores < 7, small-for-gestational-age infants and fetal malformations. Eleven studies included neonatal PCR SARS-CoV-2 testing which was performed on 129 infants, of which 20 were positive.
Conclusion.
Positive SARS-CoV-2 tested pregnant women had higher odds for preeclampsia/hypertensive disorders of pregnancy, NICU admissions, stillbirths and perinatal mortality.
Idioma: Inglés
DOI: 10.1080/14767058.2022.2051008
Año: 2022
Publicado en: Journal of Maternal-Fetal and Neonatal Medicine 35, 25 (2022), 9742-9758
ISSN: 1476-7058
Factor impacto JCR: 1.8 (2022)
Categ. JCR: OBSTETRICS & GYNECOLOGY rank: 67 / 85 = 0.788 (2022) - Q4 - T3
Factor impacto CITESCORE: 3.9 - Medicine (Q2)
Factor impacto SCIMAGO: 0.664 - Pediatrics, Perinatology and Child Health (Q2) - Obstetrics and Gynecology (Q2)
Tipo y forma: Article (Published version)
Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)
Área (Departamento): Area Anatom.Embriol.Humana (Dpto. Anatom.Histolog.Humanas)
Área (Departamento): Área Obstetricia y Ginecología (Dpto. Cirugía)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you may not distribute the modified material. Exportado de SIDERAL (2024-03-18-16:05:12)
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Este artículo se encuentra en las siguientes colecciones:
Articles > Artículos por área > Anatomía y Embriología Humana
Articles > Artículos por área > Obstetricia y Ginecología
Articles > Artículos por área > Enfermería
Record created 2023-01-26, last modified 2024-03-19