Assessment of visual function and the neuroretina in subjects diagnosed with congenital anomaly of color vision

Garcia-Martin, Elena (Universidad de Zaragoza) ; Fuentes-Bernal, Juan L ; Otin, Sofia (Universidad de Zaragoza) ; Monreal, Alida ; Cordon, Beatriz (Universidad de Zaragoza) ; Vilades, Elisa (Universidad de Zaragoza) ; Fuertes-Lazaro, Maria I (Universidad de Zaragoza)

Resumen: This cross-sectional and observational study includes 50 eyes of subjects with color blindness and 50 eyes of control subjects. Visual function (visual acuity, contrast sensitivity, and color vision) and neuroretinal structure were assessed in all subjects using optical coherence tomography (OCT). Significant thinning of the retinal nerve fiber layer, ganglion cell layer, and retina were observed in the color blindness group. Significant thinning was also recorded in layers that involve photoreceptor nuclei (between the outer limiting layer and the Bruch membrane and between the outer plexiform layer and the outer limiting membrane). OCT evaluation based on retinal segmentation is a rapid (5–10 minutes) non-invasive technique and seems to be a good biomarker of color blindness.

Idioma: Inglés

DOI: 10.1364/OE.461872

Año: 2023

Publicado en: OPTICS EXPRESS 31, 4 (2023), 5625-5639
ISSN: 1094-4087

Factor impacto JCR: 3.2 (2023)

Categ. JCR: OPTICS rank: 36 / 119 = 0.303 (2023) - Q2 - T1

Factor impacto CITESCORE: 6.6 - Atomic and Molecular Physics, and Optics (Q1)

Factor impacto SCIMAGO: 0.998 - Atomic and Molecular Physics, and Optics (Q1)

Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI17-01726
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI17-01946
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/PI20-00437
Financiación: info:eu-repo/grantAgreement/ES/MINECO-AEI-FEDER/PID2020-113281RB-C22

Tipo y forma: Article (Published version)

Área (Departamento): Área Oftalmología (Dpto. Cirugía)
Área (Departamento): Área Óptica (Dpto. Física Aplicada)