Resumen: AbstractPurposeTo investigate which morphometric and ocular surface tissue parameters are affected by short‐term soft contact lens (CL) wear and to assess whether they carry related or independent information.MethodsTwenty‐two healthy participants wore silicone hydrogel (SiHy; MyDay, CooperVision) soft CLs for 8 h in their left eye. Corneal tomography and corneoscleral topography were captured before and immediately after CL wear. Central corneal thickness (CCT), corneoscleral parameters (limbus position and corneoscleral junction [CSJ] angle) and corneal tissue parameters (corneal transparency and homogeneity) were evaluated.ResultsCorneoscleral parameters (limbus position and CSJ angle) were independent of corneal tissue parameters (transparency and homogeneity) at baseline and after CL wear. CCT was independent of all the other parameters examined at baseline, but baseline values of corneal tissue parameters were moderately correlated with CCT change (transparency: r = −0.51; p = 0.007), homogeneity: r = −0.46; p = 0.02).ConclusionsA complete characterisation of ocular surface changes following CL wear should consider corneoscleral topography and corneal densitometry simultaneously, since they carry complementary information. Idioma: Inglés DOI: 10.1111/opo.13211 Año: 2023 Publicado en: OPHTHALMIC AND PHYSIOLOGICAL OPTICS 43, 6 (2023), 1372-1378 ISSN: 0275-5408 Factor impacto JCR: 2.8 (2023) Categ. JCR: OPHTHALMOLOGY rank: 24 / 95 = 0.253 (2023) - Q2 - T1 Factor impacto CITESCORE: 5.1 - Ophthalmology (Q1) - Optometry (Q1) - Sensory Systems (Q2)