Muc17 functional maturation and expression in intestine is age-dependent
Resumen: Transmembrane mucin Muc17 is a dynamic glycoproteinexpressed in apical membranes of intestinal epithelial cells (IECs). Muc17 extends up to 1 lm into the intestinal lumen, which makes Muc17 an ideal docking site for luminal gut bacteria. However, the Muc17 function is still unknown. Our aim is to determine the role of Muc17 in the small and large intestines. Muc17 and a panel of innate immunity components were analyzed in ileum and colon of mice 0, 3, 9 14 and 24 days after birth (P0, P3, P9, P14 and P24)...
Idioma: Inglés
DOI: 10.1002/2211-5463.12675
Año: 2019
Publicado en: FEBS openbio 9, Supl. 1 (2019), 294-294
ISSN: 2211-5463

Factor impacto JCR: 2.231 (2019)
Categ. JCR: BIOCHEMISTRY & MOLECULAR BIOLOGY rank: 211 / 296 = 0.713 (2019) - Q3 - T3
Factor impacto SCIMAGO: 0.74 - Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q2)

Tipo y forma: (Published version)
Área (Departamento): Área Fisiología (Dpto. Farmacología y Fisiolog.)

Creative Commons You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.


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