000128213 001__ 128213
000128213 005__ 20241125101201.0
000128213 0247_ $$2doi$$a10.3390/bioengineering10111327
000128213 0248_ $$2sideral$$a135490
000128213 037__ $$aART-2023-135490
000128213 041__ $$aeng
000128213 100__ $$0(orcid)0000-0002-1563-9136$$aGil-Albarova, Jorge$$uUniversidad de Zaragoza
000128213 245__ $$aEvaluation of Cytocompatibility of PEEK-Based Composites as a Function of Manufacturing Processes
000128213 260__ $$c2023
000128213 5060_ $$aAccess copy available to the general public$$fUnrestricted
000128213 5203_ $$aThe biocompatible polymer polyetheretherketone (PEEK) is a suitable candidate to be part of potential all-polymer total joint replacements, provided its use is associated with better osseointegration, mechanical performance, and wear resistance. Seeking to meet the aforementioned requirements, respectively, we have manufactured a PEEK composite with different fillers: carbon fibers (CF), hydroxyapatite particles (HA) and graphene platelets (GNP). The mechanical outcomes of the composites with combinations of 0, 1.5, 3.0 wt% GNP, 5 and 15 wt% HA and 30% of wt% CF concentrations pointed out that one of the best filler combinations to achieve the previous objectives was 30 wt% CF, 8 wt% HA and 2 wt% of GNP. The study compares the bioactivity of human osteoblasts on this composite prepared by injection molding with that on the material manufactured by the Fused Filament Fabrication 3D additive technique. The results indicate that the surface adhesion and proliferation of human osteoblasts over time are better with the composite obtained by injection molding than that obtained by 3D printing. This result is more closely correlated with morphological parameters of the composite surface than its wettability behavior.
000128213 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FSE/RIS3-LMP21-18$$9info:eu-repo/grantAgreement/ES/DGA-FSE/T48-17R
000128213 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000128213 590__ $$a3.8$$b2023
000128213 592__ $$a0.627$$b2023
000128213 591__ $$aENGINEERING, BIOMEDICAL$$b44 / 123 = 0.358$$c2023$$dQ2$$eT2
000128213 593__ $$aBioengineering$$c2023$$dQ3
000128213 594__ $$a4.0$$b2023
000128213 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000128213 700__ $$aMartínez-Morlanes, María José
000128213 700__ $$aFernández, José Miguel
000128213 700__ $$aCastell, Pere
000128213 700__ $$aGracia, Luis
000128213 700__ $$0(orcid)0000-0002-3125-5802$$aPuértolas, José Antonio$$uUniversidad de Zaragoza
000128213 7102_ $$11013$$2830$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Traumatología y Ortopedia
000128213 7102_ $$15001$$2065$$aUniversidad de Zaragoza$$bDpto. Ciencia Tecnol.Mater.Fl.$$cÁrea Cienc.Mater. Ingen.Metal.
000128213 773__ $$g10, 11 (2023), 1327$$pBioengineering$$tBioengineering$$x2306-5354
000128213 8564_ $$s7617004$$uhttps://zaguan.unizar.es/record/128213/files/texto_completo.pdf$$yVersión publicada
000128213 8564_ $$s2757458$$uhttps://zaguan.unizar.es/record/128213/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000128213 909CO $$ooai:zaguan.unizar.es:128213$$particulos$$pdriver
000128213 951__ $$a2024-11-22-12:11:42
000128213 980__ $$aARTICLE