000129567 001__ 129567 000129567 005__ 20240731103323.0 000129567 0247_ $$2doi$$a10.3390/pathogens12121399 000129567 0248_ $$2sideral$$a135837 000129567 037__ $$aART-2023-135837 000129567 041__ $$aeng 000129567 100__ $$aSola, Diego$$uUniversidad de Zaragoza 000129567 245__ $$aDiagnosis in Scrapie: Conventional Methods and New Biomarkers 000129567 260__ $$c2023 000129567 5060_ $$aAccess copy available to the general public$$fUnrestricted 000129567 5203_ $$aScrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies. This review explores the challenges of scrapie diagnosis and the utility of various biomarkers and their potential implications for human prion diseases. Understanding these biomarkers in the context of scrapie may enable earlier prion disease diagnosis in humans, which is crucial for effective intervention. Research on scrapie biomarkers bridges the gap between veterinary and human medicine, offering hope for the early detection and improved management of prion diseases. 000129567 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000129567 590__ $$a3.3$$b2023 000129567 592__ $$a0.843$$b2023 000129567 591__ $$aMICROBIOLOGY$$b70 / 161 = 0.435$$c2023$$dQ2$$eT2 000129567 593__ $$aImmunology and Allergy$$c2023$$dQ2 000129567 593__ $$aImmunology and Microbiology (miscellaneous)$$c2023$$dQ2 000129567 593__ $$aMolecular Biology$$c2023$$dQ2 000129567 593__ $$aMicrobiology (medical)$$c2023$$dQ2 000129567 593__ $$aInfectious Diseases$$c2023$$dQ2 000129567 594__ $$a6.4$$b2023 000129567 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000129567 700__ $$0(orcid)0000-0002-0388-9429$$aBetancor, Marina$$uUniversidad de Zaragoza 000129567 700__ $$aMarco Lorente, Paula A.$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0002-2079-0711$$aPérez Lázaro, Sonia$$uUniversidad de Zaragoza 000129567 700__ $$aBarrio, Tomás 000129567 700__ $$0(orcid)0000-0002-4213-2904$$aSevilla, Eloisa$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0002-1590-3347$$aMarín, Belén$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0001-6629-6842$$aMoreno, Bernardino$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0002-2787-9671$$aMonzón, Marta$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0001-5105-6133$$aAcín, Cristina$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0002-2746-3932$$aBolea, Rosa$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0002-7173-7216$$aBadiola, Juan J.$$uUniversidad de Zaragoza 000129567 700__ $$0(orcid)0000-0001-9075-2764$$aOtero, Alicia$$uUniversidad de Zaragoza 000129567 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000129567 7102_ $$11003$$2443$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Histología 000129567 773__ $$g12, 12 (2023), 1399 [15 pp.]$$pPathogens$$tPathogens$$x2076-0817 000129567 8564_ $$s363474$$uhttps://zaguan.unizar.es/record/129567/files/texto_completo.pdf$$yVersión publicada 000129567 8564_ $$s2770384$$uhttps://zaguan.unizar.es/record/129567/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000129567 909CO $$ooai:zaguan.unizar.es:129567$$particulos$$pdriver 000129567 951__ $$a2024-07-31-09:43:39 000129567 980__ $$aARTICLE