Diagnosis in Scrapie: Conventional Methods and New Biomarkers

Sola, Diego (Universidad de Zaragoza) ; Betancor, Marina (Universidad de Zaragoza) ; Marco Lorente, Paula A. (Universidad de Zaragoza) ; Pérez Lázaro, Sonia (Universidad de Zaragoza) ; Barrio, Tomás ; Sevilla, Eloisa (Universidad de Zaragoza) ; Marín, Belén (Universidad de Zaragoza) ; Moreno, Bernardino (Universidad de Zaragoza) ; Monzón, Marta (Universidad de Zaragoza) ; Acín, Cristina (Universidad de Zaragoza) ; Bolea, Rosa (Universidad de Zaragoza) ; Badiola, Juan J. (Universidad de Zaragoza) ; Otero, Alicia (Universidad de Zaragoza)
Diagnosis in Scrapie: Conventional Methods and New Biomarkers
Resumen: Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies. This review explores the challenges of scrapie diagnosis and the utility of various biomarkers and their potential implications for human prion diseases. Understanding these biomarkers in the context of scrapie may enable earlier prion disease diagnosis in humans, which is crucial for effective intervention. Research on scrapie biomarkers bridges the gap between veterinary and human medicine, offering hope for the early detection and improved management of prion diseases.
Idioma: Inglés
DOI: 10.3390/pathogens12121399
Año: 2023
Publicado en: Pathogens 12, 12 (2023), 1399 [15 pp.]
ISSN: 2076-0817

Factor impacto JCR: 3.3 (2023)
Categ. JCR: MICROBIOLOGY rank: 70 / 161 = 0.435 (2023) - Q2 - T2
Factor impacto CITESCORE: 6.4 - Molecular Biology (Q2) - Infectious Diseases (Q2) - Microbiology (medical) (Q2) - Immunology and Microbiology (all) (Q2) - Immunology and Allergy (Q2)

Factor impacto SCIMAGO: 0.843 - Immunology and Allergy (Q2) - Immunology and Microbiology (miscellaneous) (Q2) - Molecular Biology (Q2) - Microbiology (medical) (Q2) - Infectious Diseases (Q2)

Tipo y forma: Article (Published version)
Área (Departamento): Área Sanidad Animal (Dpto. Patología Animal)
Área (Departamento): Area Histología (Dpto. Anatom.Histolog.Humanas)


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