Lifestyle can exert a significant impact on the development of metabolic complications and quality life in patients with inflammatory bowel disease

García-Mateo, Sandra (Universidad de Zaragoza) ; Martínez-Domínguez, Samuel J. (Universidad de Zaragoza) ; Gargallo-Puyuelo, Carla Jerusalén (Universidad de Zaragoza) ; Arroyo Villarino, María Teresa (Universidad de Zaragoza) ; Laredo De La Torre, Viviana ; Gallego, Beatriz ; Alfambra, Erika ; Gomollón, Fernando (Universidad de Zaragoza)

Resumen: Inflammatory bowel diseases (IBDs) are associated with an increased risk of metabolic comorbidities. There is a lack of data regarding the relationship between lifestyle and metabolic diseases in IBD patients. A cross-sectional study on consecutive IBD outpatients was conducted. Adherence to the Mediterranean diet (MD) was assessed using a 14-item questionnaire from the PREDIMED study, and physical activity was evaluated using the GODIN-Leisure score. Body composition was studied based on body mass index and waist–hip ratio (WHR), while quality of life was assessed using a nine-item short questionnaire. Among the 688 evaluated IBD patients, 66% were overweight or obese, 72.7% did not lead an active lifestyle and 70.1% did not adhere to the MD. Metabolic syndrome was associated with age (OR = 1.07, p = 0.019), overweight/obesity (OR = 12.987, p < 0.001) and the inflammatory behavior of Crohn’s disease (OR = 6.172, p = 0.001). Type 2 diabetes mellitus or prediabetes was associated with age (OR = 1.063 p = 0.016), overweight/obesity (OR = 3.861, p < 0.001) and the inflammatory behavior of Crohn’s disease (OR = 4.716, p = 0.001). Overweight /obesity (OR = 5.494, p < 0.001), a high WHR (OR = 2.564, p = 0.005) and a non-active lifestyle (OR = 2.202, p = 0.0003) were associated with metabolic dysfunction-associated steatotic liver disease. Lifestyle, body composition and not solely systemic inflammation might exert a significant influence on the emergence of metabolic comorbidities such as MASLD, type 2 diabetes mellitus and metabolic syndrome in patients with IBD.

Idioma: Inglés

DOI: 10.3390/nu15183983

Año: 2023

Publicado en: Nutrients 15, 18 (2023), 3983 [14 pp.]
ISSN: 2072-6643

Factor impacto JCR: 4.8 (2023)

Categ. JCR: NUTRITION & DIETETICS rank: 18 / 114 = 0.158 (2023) - Q1 - T1

Factor impacto CITESCORE: 9.2 - Food Science (Q1) - Nutrition and Dietetics (Q1)

Factor impacto SCIMAGO: 1.301 - Nutrition and Dietetics (Q1) - Food Science (Q1)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)