000130508 001__ 130508 000130508 005__ 20240125162931.0 000130508 0247_ $$2doi$$a10.1309/0t2ukukv91w3qr6w 000130508 0248_ $$2sideral$$a129741 000130508 037__ $$aART-2007-129741 000130508 041__ $$aeng 000130508 100__ $$0(orcid)0000-0003-2078-8205$$aGarcia, Mar 000130508 245__ $$aMALT Lymphoma Involving the Kidney 000130508 260__ $$c2007 000130508 5203_ $$aExtranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) can arise at any anatomic site, but involvement of the kidney is rare. We describe 10 cases of kidney MALT lymphoma, including 6 localized cases. No predisposing inflammatory conditions were identified, with the possible exception of coexistent renal Actinomyces infection in 1 case. We performed fluorescence in situ hybridization (FISH) using a malt1 break-apart probe in 7 cases. A malt1 gene rearrangement was identified in 1 case (14%). This case was further assessed by FISH using an IgH break-apart probe that showed IgH gene rearrangement. These results are suggestive of the t(14;18) involving malt1 and IgH. Immunostaining for NF- ¿B p65 showed nuclear positivity, consistent with NF- ¿B activation, in 3 of 5 cases assessed. Our results indicate that kidney MALT lymphomas share similarities with MALT lymphomas arising at other sites in that MALT lymphoma–associated translocations and NF- ¿B activation occur in a subset of cases. 000130508 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000130508 590__ $$a2.629$$b2007 000130508 591__ $$aPATHOLOGY$$b19 / 65 = 0.292$$c2007$$dQ2$$eT1 000130508 655_4 $$ainfo:eu-repo/semantics/article 000130508 700__ $$aKonoplev, Sergej 000130508 700__ $$aMorosan, Cristian 000130508 700__ $$aAbruzzo, Lynne V. 000130508 700__ $$aBueso-Ramos, Carlos E. 000130508 700__ $$aMedeiros, L. Jeffrey 000130508 773__ $$g128, 3 (2007), 464-473$$pAm. j. clin. pathol.$$tAMERICAN JOURNAL OF CLINICAL PATHOLOGY$$x0002-9173 000130508 8564_ $$s8205699$$uhttps://zaguan.unizar.es/record/130508/files/texto_completo.pdf 000130508 8564_ $$s2245405$$uhttps://zaguan.unizar.es/record/130508/files/texto_completo.jpg?subformat=icon$$xicon 000130508 909CO $$ooai:zaguan.unizar.es:130508$$particulos$$pdriver 000130508 951__ $$a2024-01-25-15:16:26 000130508 980__ $$aARTICLE