Atmospheric pressure solid analysis probe coupled to quadrupole-time of flight mass spectrometry as a tool for screening and semi-quantitative approach of polycyclic aromatic hydrocarbons, nitro-polycyclic aromatic hydrocarbons and oxo-polycyclic aromatic hydrocarbons in complex matrices

Carrizo, D. ; Domeño, C. (Universidad de Zaragoza) ; Nerín, I. (Universidad de Zaragoza) ; Alfaro, P. (Universidad de Zaragoza) ; Nerín, C. (Universidad de Zaragoza)

Resumen: A new screening and semi-quantitative approach has been developed for direct analysis of polycyclic aromatic hydrocarbons (PAHs) and their nitro and oxo derivatives in environmental and biological matrices using atmospheric pressure solid analysis probe (ASAP) quadrupole-time of flight mass spectrometry (Q-TOF-MS). The instrumental parameters were optimized for the analysis of all these compounds, without previous sample treatment, in soil, motor oil, atmospheric particles (ashes) and biological samples such as urine and saliva of smokers and non-smokers. Ion source parameters in the MS were found to be the key parameters, with little variation within PAHs families. The optimized corona current was 4 mA, sample cone voltage 80 V for PAHs, nitro-PAHs and oxo-PAHs, while the desolvation temperatures varied from 300 1C to 500 1C. The analytical method performance was checked using a certified reference material. Two deuterated compounds were used as internal standards for semi-quantitative purposes together with the pure individual standard for each compound and the corresponding calibration plot. The compounds nitro PAH 9-nitroanthracene and oxo-PAH 1,4-naphtha- lenedione, were found in saliva and urine in a range below 1 mg/g while the range of PAHs in these samples was below 2 mg/g. Environmental samples provided higher concentration of all pollutants than urine and saliva.

Idioma: Inglés

DOI: 10.1016/j.talanta.2014.07.034

Año: 2015

Publicado en: Talanta 131 (2015), 175-184
ISSN: 0039-9140

Factor impacto JCR: 4.035 (2015)

Categ. JCR: CHEMISTRY, ANALYTICAL rank: 9 / 75 = 0.12 (2015) - Q1 - T1

Factor impacto SCIMAGO: 1.173 - Chemistry (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA/T10

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Química Analítica (Dpto. Química Analítica)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
Área (Departamento): Proy. investigación HVA (Dpto. Química Analítica)