Home-based prehabilitation improves physical conditions measured by ergospirometry and 6MWT in colorectal cancer patients: a randomized controlled pilot study

Triguero-Cánovas, Daniel ; López-Rodríguez-Arias, Francisco ; Gómez-Martínez, Manuel ; Sánchez-Guillén, Luis ; Peris-Castelló, Franc ; Alcaide-Quirós, María José ; Morillas-Blasco, Pedro ; Arroyo, Antonio ; Ramírez, José Manuel (Universidad de Zaragoza)

Resumen: Purpose/background: Prehabilitation aims to improve physical condition in the preoperative period and, therefore, decrease the loss of cardiopulmonary capacity postoperatively, with the aim of reducing complications and promoting an early recovery. This study aims to evaluate the impact of home-based prehabilitation on the physical condition of patients treated surgically for colorectal cancer. Methods: A prospective and randomized clinical study was conducted on 60 patients during two periods from October 2018 to February 2019 and from September 2019 to September 2020, in a single university hospital. Patients were randomized into two study groups (30 per group): prehabilitation vs. standard care. Changes in physical condition, measured at diagnosis, the day before surgery, and at 6–8 weeks after surgery using the cardiopulmonary exercise testing (CPET) and the 6-minute walk test (6MWT) were evaluated. Results: Prehabilitation reduced postoperative complications (17.4% vs. 33.3%, p = 0.22) and hospital stay (5.74 vs. 6.67 days, p = 0.30). 6MWT showed a significant improvement in the prehabilitation group (+78.9 m). Six weeks after surgery, prehabilitation showed a significant improvement in the 6MWT (+68.9 m vs. −27.2 m, p = 0.01). Significant differences were also observed in the ergospirometry between the diagnosis and postoperative study (+0.79 METs vs. −0.84 METs, p = 0.001). A strong correlation was observed between CPET and 6MWT (0.767 (p < 0.001)). Conclusion: Home prehabilitation achieved lower overall postoperative complications than standard care and reached significant improvements in 6MWT and CET. A strong correlation was observed between CET and 6MWT, which allows validation of 6MWT as a valid and reliable measure of functional exercise capacity in colorectal patients when other, more specific and expensive tests are not available.

Idioma: Inglés

DOI: 10.1007/s00520-023-08140-4

Año: 2023

Publicado en: SUPPORTIVE CARE IN CANCER 31 (2023), 673 [9 pp.]
ISSN: 0941-4355

Factor impacto JCR: 2.8 (2023)

Categ. JCR: REHABILITATION rank: 16 / 170 = 0.094 (2023) - Q1 - T1
Categ. JCR: HEALTH CARE SCIENCES & SERVICES rank: 57 / 174 = 0.328 (2023) - Q2 - T1
Categ. JCR: ONCOLOGY rank: 157 / 322 = 0.488 (2023) - Q2 - T2

Factor impacto CITESCORE: 5.7 - Rehabilitation (Q1) - Oncology (nursing) (Q1) - Oncology (Q2)

Factor impacto SCIMAGO: 1.007 - Oncology (nursing) (Q1) - Rehabilitation (Q1) - Oncology (Q2)

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Cirugía (Dpto. Cirugía)