000132107 001__ 132107 000132107 005__ 20240301161205.0 000132107 0247_ $$2doi$$a10.1021/jacs.1c04115 000132107 0248_ $$2sideral$$a131576 000132107 037__ $$aART-2021-131576 000132107 041__ $$aeng 000132107 100__ $$0(orcid)0000-0002-8932-9085$$aConcellón, Alberto 000132107 245__ $$aComplex liquid crystal emulsions for biosensing 000132107 260__ $$c2021 000132107 5060_ $$aAccess copy available to the general public$$fUnrestricted 000132107 5203_ $$aHerein we describe a highly responsive optical biosensor based on dynamic complex liquid crystal (LC) emulsions. These emulsions are simple to prepare and consist of immiscible chiral nematic liquid crystals (N*) and fluorocarbon oils. In this work, we exploit the N* selective reflection to build a new sensing paradigm. Our detection strategy is based on changes in the LC/water interfacial activity of boronic acid polymeric surfactants caused by reversible interactions with IgG antibodies at the LC interface. Such biomolecular recognition events can vary the pitch length of the N* organization due to the presence of binaphthyl units in the polymeric structure, which are known to be powerful chiral dopants. We demonstrate that these interface-triggered reflection changes can be used as an effective optical read-out for the detection of the foodborne pathogen Salmonella. 000132107 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000132107 590__ $$a16.383$$b2021 000132107 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b16 / 179 = 0.089$$c2021$$dQ1$$eT1 000132107 592__ $$a5.728$$b2021 000132107 593__ $$aBiochemistry$$c2021$$dQ1 000132107 593__ $$aColloid and Surface Chemistry$$c2021$$dQ1 000132107 593__ $$aCatalysis$$c2021$$dQ1 000132107 594__ $$a25.2$$b2021 000132107 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000132107 700__ $$aFong, Darryl 000132107 700__ $$aSwager, Timothy M. 000132107 773__ $$g143, 24 (2021), 9177-9182$$pJ. Am. Chem. Soc.$$tJournal of the American Chemical Society$$x0002-7863 000132107 8564_ $$s1241940$$uhttps://zaguan.unizar.es/record/132107/files/texto_completo.pdf$$yPostprint 000132107 8564_ $$s2917375$$uhttps://zaguan.unizar.es/record/132107/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000132107 909CO $$ooai:zaguan.unizar.es:132107$$particulos$$pdriver 000132107 951__ $$a2024-03-01-14:46:27 000132107 980__ $$aARTICLE