000132318 001__ 132318 000132318 005__ 20241125101156.0 000132318 0247_ $$2doi$$a10.1016/j.fitote.2023.105696 000132318 0248_ $$2sideral$$a137411 000132318 037__ $$aART-2023-137411 000132318 041__ $$aeng 000132318 100__ $$aDjebari, Sabrina 000132318 245__ $$aPhenolic compounds profile of macerates of different edible parts of carob tree (Ceratonia siliqua L.) using UPLC-ESI-Q-TOF-MSE: Phytochemical screening and biological activities 000132318 260__ $$c2023 000132318 5203_ $$aLocust bean pulp and gum extracts were prepared, and phytochemical tests based on color reactions and chromatographic analyzes were performed. A profile of seventy-six phenolic compounds was obtained by the ultra-high performance liquid chromatography with electrospray ionization and quadrupole time-of-flight mass spectrometry. The main groups of phenolic compounds identified in the both extracts of Ceratonia siliqua L., were flavonoids, tannins and phenolic acids. Moreover, carob pulp and gum extracts were tested for their antimicrobial activity using disk diffusion tests which showed sensitivity of the different strains to the analyzed extracts at a concentration of 100 mg/mL. Additionally, the antioxidant activity of Ceratonia siliqua L. extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl acid test, which confirmed stronger antioxidant properties in the case of the pulp extract. To sum up, carob pulp and gum extracts present promising alternatives to synthetic additives within the medicinal industry, serving as potential antioxidant agents and preservatives that combat bacterial contamination, thereby offering a more natural approach to enhancing product safety and efficacy. 000132318 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/RTI2018-097805-B-I00 000132318 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000132318 590__ $$a2.5$$b2023 000132318 592__ $$a0.572$$b2023 000132318 591__ $$aPHARMACOLOGY & PHARMACY$$b180 / 354 = 0.508$$c2023$$dQ3$$eT2 000132318 593__ $$aDrug Discovery$$c2023$$dQ2 000132318 591__ $$aCHEMISTRY, MEDICINAL$$b47 / 72 = 0.653$$c2023$$dQ3$$eT2 000132318 593__ $$aMedicine (miscellaneous)$$c2023$$dQ2 000132318 593__ $$aPharmacology$$c2023$$dQ3 000132318 594__ $$a5.8$$b2023 000132318 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000132318 700__ $$0(orcid)0000-0003-2052-3012$$aWrona, Magdalena$$uUniversidad de Zaragoza 000132318 700__ $$0(orcid)0000-0003-2685-5739$$aNerín, Cristina$$uUniversidad de Zaragoza 000132318 700__ $$aDjaoudene, Ouarda 000132318 700__ $$aGuemouni, Sara 000132318 700__ $$aBoudria, Asma 000132318 700__ $$aMadani, Khodir 000132318 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica 000132318 773__ $$g172 (2023), 105696 [20 pp.]$$pFitoterapia$$tFITOTERAPIA$$x0367-326X 000132318 8564_ $$s1596434$$uhttps://zaguan.unizar.es/record/132318/files/texto_completo.pdf$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2024-10-04 000132318 8564_ $$s2475883$$uhttps://zaguan.unizar.es/record/132318/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2024-10-04 000132318 909CO $$ooai:zaguan.unizar.es:132318$$particulos$$pdriver 000132318 951__ $$a2024-11-22-12:09:15 000132318 980__ $$aARTICLE