Phenolic compounds profile of macerates of different edible parts of carob tree (Ceratonia siliqua L.) using UPLC-ESI-Q-TOF-MSE: Phytochemical screening and biological activities
Djebari, Sabrina ; Wrona, Magdalena (Universidad de Zaragoza) ; Nerín, Cristina (Universidad de Zaragoza) ; Djaoudene, Ouarda ; Guemouni, Sara ; Boudria, Asma ; Madani, Khodir
Resumen: Locust bean pulp and gum extracts were prepared, and phytochemical tests based on color reactions and chromatographic analyzes were performed. A profile of seventy-six phenolic compounds was obtained by the ultra-high performance liquid chromatography with electrospray ionization and quadrupole time-of-flight mass spectrometry. The main groups of phenolic compounds identified in the both extracts of Ceratonia siliqua L., were flavonoids, tannins and phenolic acids.
Moreover, carob pulp and gum extracts were tested for their antimicrobial activity using disk diffusion tests which showed sensitivity of the different strains to the analyzed extracts at a concentration of 100 mg/mL. Additionally, the antioxidant activity of Ceratonia siliqua L. extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl acid test, which confirmed stronger antioxidant properties in the case of the pulp extract.
To sum up, carob pulp and gum extracts present promising alternatives to synthetic additives within the medicinal industry, serving as potential antioxidant agents and preservatives that combat bacterial contamination, thereby offering a more natural approach to enhancing product safety and efficacy.
Idioma: Inglés
DOI: 10.1016/j.fitote.2023.105696
Año: 2023
Publicado en: FITOTERAPIA 172 (2023), 105696 [20 pp.]
ISSN: 0367-326X
Factor impacto JCR: 2.5 (2023)
Categ. JCR: PHARMACOLOGY & PHARMACY rank: 180 / 354 = 0.508 (2023) - Q3 - T2
Categ. JCR: CHEMISTRY, MEDICINAL rank: 47 / 72 = 0.653 (2023) - Q3 - T2
Factor impacto CITESCORE: 5.8 - Drug Discovery (Q2) - Pharmacology (Q2)
Factor impacto SCIMAGO: 0.572 - Drug Discovery (Q2) - Medicine (miscellaneous) (Q2) - Pharmacology (Q3)
Financiación: info:eu-repo/grantAgreement/ES/MINECO/RTI2018-097805-B-I00
Tipo y forma: Artículo (PostPrint)
Área (Departamento): Área Química Analítica (Dpto. Química Analítica)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial. Si remezcla, transforma o crea a partir del material, no puede difundir el material modificado.
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Moreover, carob pulp and gum extracts were tested for their antimicrobial activity using disk diffusion tests which showed sensitivity of the different strains to the analyzed extracts at a concentration of 100 mg/mL. Additionally, the antioxidant activity of Ceratonia siliqua L. extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl acid test, which confirmed stronger antioxidant properties in the case of the pulp extract.
To sum up, carob pulp and gum extracts present promising alternatives to synthetic additives within the medicinal industry, serving as potential antioxidant agents and preservatives that combat bacterial contamination, thereby offering a more natural approach to enhancing product safety and efficacy.
Idioma: Inglés
DOI: 10.1016/j.fitote.2023.105696
Año: 2023
Publicado en: FITOTERAPIA 172 (2023), 105696 [20 pp.]
ISSN: 0367-326X
Factor impacto JCR: 2.5 (2023)
Categ. JCR: PHARMACOLOGY & PHARMACY rank: 180 / 354 = 0.508 (2023) - Q3 - T2
Categ. JCR: CHEMISTRY, MEDICINAL rank: 47 / 72 = 0.653 (2023) - Q3 - T2
Factor impacto CITESCORE: 5.8 - Drug Discovery (Q2) - Pharmacology (Q2)
Factor impacto SCIMAGO: 0.572 - Drug Discovery (Q2) - Medicine (miscellaneous) (Q2) - Pharmacology (Q3)
Financiación: info:eu-repo/grantAgreement/ES/MINECO/RTI2018-097805-B-I00
Tipo y forma: Artículo (PostPrint)
Área (Departamento): Área Química Analítica (Dpto. Química Analítica)
Debe reconocer adecuadamente la autoría, proporcionar un enlace a la licencia e indicar si se han realizado cambios. Puede hacerlo de cualquier manera razonable, pero no de una manera que sugiera que tiene el apoyo del licenciador o lo recibe por el uso que hace. No puede utilizar el material para una finalidad comercial. Si remezcla, transforma o crea a partir del material, no puede difundir el material modificado.Exportado de SIDERAL (2024-07-31-10:02:49)
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