The utility of fetal heart rate deceleration's descending slope in searching for a non-National Institute of Child Health and Human Development parameter for the detection of fetal acidosis

Castan Larraz, Berta ; Esteban, Luis Mariano ; Castán Mateo, Sergio (Universidad de Zaragoza) ; Chóliz Ezquerro, Marta ; Calvo Torres, Javier ; Esteban-Escaño, Javier ; Rodríguez Solanilla, Belén (Universidad de Zaragoza) ; Cisneros Gimeno, Ana (Universidad de Zaragoza) ; Savirón-Cornudella, Ricardo

Resumen: AbstractObjectiveTo identify new parameters predicting fetal acidemia.MethodsA retrospective case–control study in a cohort of deliveries from a tertiary referral hospital‐based cohort deliveries in Zaragoza, Spain between 2018 and 2021 was performed. To predict fetal acidemia, the NICHD categorizations and non‐NICHD parameters were analyzed in the electronic fetal monitoring (EFM). Those included total reperfusion time, total deceleration area and the slope of the descending limb of the fetal heart rate of the last deceleration curve. The accuracy of the parameters was evaluated using the specificity for (80%, 85%, 90%, 95%) sensitivity and the area under the receiver operating characteristic curve (AUC).ResultsA total of 10 362 deliveries were reviewed, with 224 cases and 278 controls included in the study. The NICHD categorizations showed reasonable discriminatory ability (AUC = 0.727). The non‐NICHD parameters measured during the 30‐min fetal monitoring, total deceleration area (AUC = 0.807, 95% CI: 0.770, 0.845) and total reperfusion time (AUC = 0.750, 95% CI: 0.707, 0.792), exhibited higher discriminatory ability. The slope of the descending limb of the fetal heart rate of the last deceleration curve had the best AUC value (0.853, 95% CI: 0.816, 0.889). The combination of total deceleration area or total reperfusion time with the slope demonstrated high discriminatory ability (AUC = 0.908, 95% CI: 0.882, 0.933; specificities of 71.6% and 72.7% for a sensitivity of 90%).ConclusionsThe slope of the descending limb of the fetal heart rate of the last deceleration curve is the strongest predictor of fetal acidosis, but its combination with the total reperfusion time shows better clinical utility.

Idioma: Inglés

DOI: 10.1002/ijgo.15454

Año: 2024

Publicado en: International Journal of Gynecology and Obstetrics 166, 2 (2024), 859-870
ISSN: 0020-7292

Financiación: info:eu-repo/grantAgreement/ES/DGA/T69-23R

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Area Anatom.Embriol.Humana (Dpto. Anatom.Histolog.Humanas)
Área (Departamento): Área Obstetricia y Ginecología (Dpto. Cirugía)