An immersive virtual reality-based object-location memory task reveals spatial long-term memory alterations in Long-COVID
Llana, Tania ; Garcés-Arilla, Sara (Universidad de Zaragoza) ; Juan, M. Carmen ; Méndez-López, Magdalena (Universidad de Zaragoza) ; Méndez, Marta
Resumen: Object-location memory (OLM) is a type of declarative memory for spatial information and consists of the individual's ability to establish accurate associations between objects and their spatial locations. Long-COVID describes the long-term effects of the COVID-19 disease. Long-COVID patients show medial temporal lobe dysfunction and neuropsychological alterations affecting memory. This study aimed to assess OLM in a group of Long-COVID patients, n=66, and a Control group of healthy individuals with similar age and sex composition, n=21, using an immersive virtual reality (iVR)-based OLM task. We also explored associations between the performance in the iVR-based OLM task and general cognitive function (MoCA), and both verbal (VSTM) and visuospatial (SSTM) span. The Long-COVID group showed fewer correct responses, made more task attempts, and invested more time in the iVR-based OLM task than the Control group. Delayed memory was more severely altered than immediate memory in Long-COVID participants. Better MoCA scores of the Long-COVID group were strongly associated with shorter times to complete the immediate recall of the iVR-based OLM task. Besides, the months elapsed since the COVID-19 infection were slightly associated with fewer correct responses in the immediate and 24-hour recalls. These results corroborate previous findings of memory alterations in the Long-COVID syndrome using an iVR-based OLM task, adding new evidence on spatial memory and long-term memory in this population. Implementing spatial iVR tasks to clinical research may improve our understanding of neuropsychological disorders.
Idioma: Inglés
DOI: 10.1016/j.bbr.2024.115127
Año: 2024
Publicado en: Behavioural brain research 471 (2024), 115127 [12 pp.]
ISSN: 0166-4328
Factor impacto JCR: 2.3 (2024)
Categ. JCR: BEHAVIORAL SCIENCES rank: 21 / 57 = 0.368 (2024) - Q2 - T2
Categ. JCR: NEUROSCIENCES rank: 213 / 314 = 0.678 (2024) - Q3 - T3
Factor impacto SCIMAGO: 0.919 - Behavioral Neuroscience (Q2)
Financiación: info:eu-repo/grantAgreement/ES/DGA/S31-23R
Financiación: info:eu-repo/grantAgreement/ES/NextGenerationEU/INVESTIGO-067-38
Tipo y forma: Article (Published version)
Área (Departamento): Área Psicobiología (Dpto. Psicología y Sociología)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2025-09-22-14:43:43)
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Idioma: Inglés
DOI: 10.1016/j.bbr.2024.115127
Año: 2024
Publicado en: Behavioural brain research 471 (2024), 115127 [12 pp.]
ISSN: 0166-4328
Factor impacto JCR: 2.3 (2024)
Categ. JCR: BEHAVIORAL SCIENCES rank: 21 / 57 = 0.368 (2024) - Q2 - T2
Categ. JCR: NEUROSCIENCES rank: 213 / 314 = 0.678 (2024) - Q3 - T3
Factor impacto SCIMAGO: 0.919 - Behavioral Neuroscience (Q2)
Financiación: info:eu-repo/grantAgreement/ES/DGA/S31-23R
Financiación: info:eu-repo/grantAgreement/ES/NextGenerationEU/INVESTIGO-067-38
Tipo y forma: Article (Published version)
Área (Departamento): Área Psicobiología (Dpto. Psicología y Sociología)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2025-09-22-14:43:43)
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Record created 2024-07-19, last modified 2025-09-23