000145386 001__ 145386
000145386 005__ 20241024135331.0
000145386 0247_ $$2doi$$a10.1007/s11356-024-34983-3
000145386 0248_ $$2sideral$$a140271
000145386 037__ $$aART-2024-140271
000145386 041__ $$aeng
000145386 100__ $$aGarralaga, Mª Pilar
000145386 245__ $$aAssessment of oxidative stress biomarkers in Palaemon varians exposed to deep eutectic systems
000145386 260__ $$c2024
000145386 5060_ $$aAccess copy available to the general public$$fUnrestricted
000145386 5203_ $$aIn recent years, there has been extensive research within the scientific community on deep eutectic systems due to their remarkable versatility in solubilizing diverse substances and serving as effective solvents in catalytic processes. While initially regarded as non-toxic, a comprehensive toxicological assessment is essential to comprehend their behavior within organisms. In this study, seven distinct systems, composed of N,N,N-triethyl-N-(2,3-dihydroxypropyl)ammonium chloride (N00Cl) and glycerol-derived ethers with alkyl chains of varying lengths (100, 200, 3F00, 300, 3i00, and 400), in a 1:2 molar ratio were investigated for their aquatic toxicity in shrimp (Palaemon varians). The assessment involved analyzing oxidative stress biomarkers such as glutathione S-transferase, glutathione peroxidase, catalase, superoxide dismutase, total antioxidant capacity (TAC), and lipoperoxidation (MDA content). Results show an odd–even effect for LC50 values being N00Cl-300, the system showing higher values. Regarding oxidative stress, an imbalance between reactive oxygen species (ROS) and antioxidant capacity in the organisms has been observed, suggesting significant toxicity to shrimps due to the changes in oxidative stress biomarkers at high concentrations. However, at 100 mg/l all systems can be considered environmentally safe, and no negative impacts are expected on aquatic ecosystems.
000145386 536__ $$9info:eu-repo/grantAgreement/ES/DGA/B58-23R$$9info:eu-repo/grantAgreement/ES/DGA/E37-23R$$9info:eu-repo/grantAgreement/EC/H2020/725034/EU/ When solids become liquids: natural deep eutectic solvents for chemical process engineering/Des.solve$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 725034-Des.solve$$9info:eu-repo/grantAgreement/ES/MINECO/PID2020-125762NB-I00
000145386 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000145386 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000145386 700__ $$aFerreira, Ines
000145386 700__ $$aLomba, Laura
000145386 700__ $$0(orcid)0000-0002-2676-8814$$aPires, Elisabet$$uUniversidad de Zaragoza
000145386 700__ $$aGracia-Barberán, Sara
000145386 700__ $$aDuarte, Ana Rita C.
000145386 700__ $$aDiniz, Mário
000145386 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000145386 773__ $$g31, 47 (2024), 57959-57972$$pEnviron. sci. pollut. res. int.$$tEnvironmental Science and Pollution Research$$x0944-1344
000145386 8564_ $$s3375955$$uhttps://zaguan.unizar.es/record/145386/files/texto_completo.pdf$$yVersión publicada
000145386 8564_ $$s2437410$$uhttps://zaguan.unizar.es/record/145386/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000145386 909CO $$ooai:zaguan.unizar.es:145386$$particulos$$pdriver
000145386 951__ $$a2024-10-24-12:11:49
000145386 980__ $$aARTICLE