Adhesion of Catechol-Functionalized Linear-Dendritic Block Copolymers: dendritic effect, self-assembly, and bioadhesion
Lancelot, Alexandre ; Meger, Mitchell E. ; Guerreiro Gómez, Enrique (Universidad de Zaragoza) ; Sierra, Teresa ; Wilker, Jonathan J.
Resumen: Inspired by mussels protein adhesives, two series of catechol‐functionalized Linear‐Dendritic Block Copolymer (LDBC) adhesives are synthesized. They show lap shear adhesion strength as high as 7 MPa on aluminum substrates and adhesion up to 3 kPa on porcine skin. These water‐soluble LDBCs are composed of i) either poly(ethylene glycol) (PEG) or poly(ethylene glycol)‐poly(propylene glycol)‐poly(ethylene glycol) triblock copolymer (Pluronic F‐127) as linear polymers, ii) Bis‐MPA dendrons of generation 0, 1, and 2 as dendritic parts, and iii) 2, 4, or 8 terminal catechol moieties. A LDBCs generation comparative test on aluminum reveals a clear dendritic effect: the LDBCs of second generation display higher adhesion than the LDBCs of first generation that also display higher adhesion than the LDBCs of generation 0 for both series, assessing thus a positive dendritic effect in adhesion. Second, a comparative study is carried out between the LDBCs based on PEG and the ones based on Pluronic. The ability of the Pluronic LDBCs to self‐assemble in water appears to reduce adhesion when applied on aluminum whereas it is essential to obtain adhesion on porcine skin, thanks to the formation of hydrogels, as observed by the vial inversion technique and electron microscopy.
Idioma: Inglés
DOI: 10.1002/adfm.202413398
Año: 2024
Publicado en: Advanced Functional Materials (2024), 2413398 [15 pp.]
ISSN: 1616-301X
Financiación: info:eu-repo/grantAgreement/ES/AEI/CEX2023-001286-S
Financiación: info:eu-repo/grantAgreement/ES/DGA/E47-23R
Financiación: info:eu-repo/grantAgreement/EC/H2020/101062504/EU/info:eu-repo/grantAgreement/EC/H2020/101062504/EU//DAHAD/DAHAD
Financiación: info:eu-repo/grantAgreement/ES/MICINN/PID2021-126132NB-I00
Tipo y forma: Article (Published version)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2024-12-20-12:02:43)
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Idioma: Inglés
DOI: 10.1002/adfm.202413398
Año: 2024
Publicado en: Advanced Functional Materials (2024), 2413398 [15 pp.]
ISSN: 1616-301X
Financiación: info:eu-repo/grantAgreement/ES/AEI/CEX2023-001286-S
Financiación: info:eu-repo/grantAgreement/ES/DGA/E47-23R
Financiación: info:eu-repo/grantAgreement/EC/H2020/101062504/EU/info:eu-repo/grantAgreement/EC/H2020/101062504/EU//DAHAD/DAHAD
Financiación: info:eu-repo/grantAgreement/ES/MICINN/PID2021-126132NB-I00
Tipo y forma: Article (Published version)
Área (Departamento): Área Química Orgánica (Dpto. Química Orgánica)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2024-12-20-12:02:43)
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Record created 2024-12-20, last modified 2024-12-20