Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs

Alférez, María Dolores ; Corda, Andrea ; de Blas, Ignacio (Universidad de Zaragoza) ; Gago, Lucas ; Fernandes, Telmo ; Rodríguez-Piza, Ignacio ; Balañá, Beatriz ; Pentcheva, Plamena ; Caruncho, Javier ; Barbero-Fernández, Alicia ; Llinás, Jorge ; Rivas, David ; Escudero, Amaia ; Gómez-Ochoa, Pablo (Universidad de Zaragoza)

Resumen: Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.

Idioma: Inglés

DOI: 10.3390/ani14243682

Año: 2024

Publicado en: Animals 14, 24 (2024), 3682 [14 pp.]
ISSN: 2076-2615

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Sanidad Animal (Dpto. Patología Animal)
Área (Departamento): Área Medicina y Cirugía Animal (Dpto. Patología Animal)