Association between alcohol consumption and subclinical femoral atherosclerosis in smoking and non-smoking men: The AWHS Study
Moreno-Franco, Belén (Universidad de Zaragoza) ; Pérez-Esteban, Alejandro ; Civeira, Fernando (Universidad de Zaragoza) ; Guallar-Castillón, Pilar ; Casasnovas, José Antonio (Universidad de Zaragoza) ; Mateo-Gállego, Rocío (Universidad de Zaragoza) ; Jarauta, Estíbaliz (Universidad de Zaragoza) ; Malo, Sara (Universidad de Zaragoza) ; Laclaustra, Martín (Universidad de Zaragoza)
Resumen: Background and Aims: Many addictive substances, such as tobacco and alcohol, influence atherosclerosis development. Whether or not tobacco's pro-atherosclerotic effect is influenced by alcohol consumption is unknown. We aimed to estimate the impact of alcohol intake on the presence of subclinical atherosclerosis in femoral arteries in smoking and non-smoking middle-aged men.Design, Setting and Participants: Cross-sectional analysis of a subset of the Aragon Workers Health Study (AWHS), comprising 2099 men with mean age 50.9 years without previous cardiovascular disease. Measurements: The presence of plaques in femoral arteries was assessed by high-resolution sonography. Self-reported alcohol consumption over the previous year was measured with a food frequency questionnaire. The sample was divided into four groups according to their daily grams of alcohol consumption = 1 (abstainers), = 2 to < 30, = 30 to < 60 and = 60 g/day. Participants were divided on ever-smoking (current and former) versus never-smoking strata in the main analysis. Findings: We did not find a significant association between the different levels of alcohol intake and the likelihood of developing femoral artery atherosclerosis in never-smokers. Ever-smoking was positively associated with femoral atherosclerosis overall [odds ratio (OR) = 3.00; 95% confidence interval (CI) = 2.40, 3.74; P < 0.001] and within each level of alcohol consumption. Atherosclerosis was lower in ever-smokers who consumed 2 g/day or more but less than 30 g/day with respect to those ever-smokers who were abstainers (OR = 0.70; 95% CI = 0.49, 0.99; P < 0.05). However, among these ever-smokers, atherosclerosis prevalence was still higher than among never-smokers who consumed alcohol in the same amount (2 g/day or more but less than 30 g/day) (OR = 2.73; 95% CI = 2.07, 3.61; P < 0.001). Conclusions: Among middle-aged men, moderate alcohol consumption appears to be associated with lower prevalence of femoral artery subclinical atherosclerosis compared with alcohol abstinence only in ever-smokers.
Idioma: Inglés
DOI: 10.1111/add.15012
Año: 2020
Publicado en: ADDICTION 115, 9 (2020), 1754-1761
ISSN: 0965-2140
Factor impacto JCR: 6.526 (2020)
Categ. JCR: PSYCHIATRY rank: 21 / 155 = 0.135 (2020) - Q1 - T1
Categ. JCR: SUBSTANCE ABUSE rank: 3 / 37 = 0.081 (2020) - Q1 - T1
Categ. JCR: PSYCHIATRY rank: 14 / 142 = 0.099 (2020) - Q1 - T1
Categ. JCR: SUBSTANCE ABUSE rank: 2 / 21 = 0.095 (2020) - Q1 - T1
Factor impacto SCIMAGO: 2.423 - Psychiatry and Mental Health (Q1) - Medicine (miscellaneous) (Q1)
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI17-10704
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI18-01929
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
Área (Departamento): Área Medic.Prevent.Salud Públ. (Dpto. Microb.Ped.Radio.Sal.Pú.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
Exportado de SIDERAL (2025-01-13-14:27:34)
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Idioma: Inglés
DOI: 10.1111/add.15012
Año: 2020
Publicado en: ADDICTION 115, 9 (2020), 1754-1761
ISSN: 0965-2140
Factor impacto JCR: 6.526 (2020)
Categ. JCR: PSYCHIATRY rank: 21 / 155 = 0.135 (2020) - Q1 - T1
Categ. JCR: SUBSTANCE ABUSE rank: 3 / 37 = 0.081 (2020) - Q1 - T1
Categ. JCR: PSYCHIATRY rank: 14 / 142 = 0.099 (2020) - Q1 - T1
Categ. JCR: SUBSTANCE ABUSE rank: 2 / 21 = 0.095 (2020) - Q1 - T1
Factor impacto SCIMAGO: 2.423 - Psychiatry and Mental Health (Q1) - Medicine (miscellaneous) (Q1)
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI17-10704
Financiación: info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI18-01929
Tipo y forma: Article (PostPrint)
Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
Área (Departamento): Área Medic.Prevent.Salud Públ. (Dpto. Microb.Ped.Radio.Sal.Pú.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2025-01-13-14:27:34)
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Record created 2025-01-13, last modified 2025-01-14