Heterobimetallic complexes for theranostic applications

Fernández-Moreira, Vanesa ; Gimeno, M.Concepción (Universidad de Zaragoza)

Resumen: The design of more efficient anticancer drugs requires a deeper understanding of their biodistribution and mechanism of action. Cell imaging agents could help to gain insight into biological processes and, consequently, the best strategy for attaining suitable scaffolds in which both biological and imaging properties are maximized. A new concept arises in this field that is the combination of two metal fragments as collaborative partners to provide the precise emissive properties to visualize the cell as well as the optimum cytotoxic activity to build more potent and selective chemotherapeutic agents.

Idioma: Inglés

DOI: 10.1002/chem.201705335

Año: 2018

Publicado en: Chemistry - A European Journal 24, 14 (2018), 3345-3353
ISSN: 0947-6539

Factor impacto JCR: 5.16 (2018)

Categ. JCR: CHEMISTRY, MULTIDISCIPLINARY rank: 36 / 172 = 0.209 (2018) - Q1 - T1

Factor impacto SCIMAGO: 1.842 - Catalysis (Q1) - Organic Chemistry (Q1) - Chemistry (miscellaneous) (Q1)

Financiación: info:eu-repo/grantAgreement/ES/DGA-FSE/E77
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2015-70371-REDT
Financiación: info:eu-repo/grantAgreement/ES/MINECO-FEDER/CTQ2016-75816-C2-1-P

Tipo y forma: Article (PostPrint)

Área (Departamento): Área Química Inorgánica (Dpto. Química Inorgánica)