000148538 001__ 148538
000148538 005__ 20250120165541.0
000148538 0247_ $$2doi$$a10.1016/j.canep.2014.05.002
000148538 0248_ $$2sideral$$a87697
000148538 037__ $$aART-2014-87697
000148538 041__ $$aeng
000148538 100__ $$aEsteva, M.
000148538 245__ $$aAge differences in presentation, diagnosis pathway and management of colorectal cancer
000148538 260__ $$c2014
000148538 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148538 5203_ $$aBACKGROUND: The gap in survival between older and younger European cancer patients is getting wider. It is possible that cancer in the elderly is being managed or treated differently than in their younger counterparts. This study aims to explore age disparities with respect to the clinical characteristics of the tumour, diagnostic pathway and treatment of colorectal cancer patients.
METHODS: We conducted a multicenter cross sectional study in 5 Spanish regions. Consecutive incident cases of CRC were identified from pathology services.
MEASUREMENTS: From patient interviews, hospital and primary care clinical records, we collected data on symptoms, stage, doctors investigations, time duration to diagnosis/treatment, quality of care and treatment.
RESULTS: 777 symptomatic cases, 154 were older than 80 years. Stage was similar by age group. General symptoms were more frequent in the eldest and abdominal symptoms in the youngest. No differences were found regarding perception of symptom seriousness and symptom disclosure between age groups as no longer duration to diagnosis or treatment was observed in the oldest groups. In primary care, only ultrasound is more frequently ordered in those <65 years. Those >80 years had a significantly higher proportion of iron testing and abdominal XR requested in hospital. We observed a high resection rate independently of age but less adjuvant chemotherapy in Stage III colon cancer, and of radiotherapy in stage II and III rectal cancer as age increases.
CONCLUSION: There are no relevant age disparities in the CRC diagnosis process with similar stage, duration to diagnosis, investigations and surgery. However, further improvements have to be made with respect to adjuvant therapy.
000148538 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/PI050700$$9info:eu-repo/grantAgreement/ES/ISCIII/PI050787$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052141$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052273$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052692$$9info:eu-repo/grantAgreement/ES/ISCIII/RD06-0018$$9info:eu-repo/grantAgreement/ES/ISCIII-RETCI/RD12-0005-0011$$9info:eu-repo/grantAgreement/ES/ISCIII-RETCI/G03-170
000148538 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000148538 590__ $$a2.711$$b2014
000148538 591__ $$aPUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH$$b38 / 164 = 0.232$$c2014$$dQ1$$eT1
000148538 591__ $$aONCOLOGY$$b115 / 209 = 0.55$$c2014$$dQ3$$eT2
000148538 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000148538 700__ $$aRuiz, A.
000148538 700__ $$aRamos, M.
000148538 700__ $$aCasamitjana, M.
000148538 700__ $$0(orcid)0000-0001-8756-114X$$aSánchez-Calavera, M.A.$$uUniversidad de Zaragoza
000148538 700__ $$aGonzález-Luján, L.
000148538 700__ $$aPita-Fernández, S.
000148538 700__ $$aLeiva, A.
000148538 700__ $$aPértega-Díaz, S.
000148538 700__ $$aCosta-Alcaraz, A.
000148538 700__ $$aMacià, F.
000148538 700__ $$aEspí, A.
000148538 700__ $$aSegura, J.M.
000148538 700__ $$aLafita, S.
000148538 700__ $$aNovella, M.T.
000148538 700__ $$aYus, C.
000148538 700__ $$aOliván, B.
000148538 700__ $$aCabeza, E.
000148538 700__ $$aSeoane-Pillado, T.
000148538 700__ $$aLópez-Calviño, B.
000148538 700__ $$aLlobera, J.
000148538 700__ $$aMartín-Rabadán, M. Maria
000148538 700__ $$aTeresa Novella, M.
000148538 700__ $$aRipoll, J.
000148538 700__ $$aManzano, H.
000148538 700__ $$aAmengual, I.
000148538 700__ $$aForteza, A.
000148538 700__ $$aCompany, M.
000148538 700__ $$aLluch Bennassar, Maria de
000148538 700__ $$aSánchez, M.A.
000148538 700__ $$aMagallón, R.
000148538 700__ $$0(orcid)0000-0001-6565-9699$$aOlivan, B.$$uUniversidad de Zaragoza
000148538 700__ $$aMaciá, F.
000148538 700__ $$aPita, S.
000148538 700__ $$aPertega-Díaz, S.
000148538 700__ $$aLouro, A.
000148538 700__ $$aSerrano, J.
000148538 700__ $$aArnal, F.
000148538 700__ $$aGonzález-Santamaría, P.
000148538 700__ $$aSeoane, T.
000148538 700__ $$aGonzález-Lujan, L.
000148538 700__ $$aCosta-Alcaraz, A.
000148538 700__ $$aEspí, I.
000148538 700__ $$aBosca, M.M.
000148538 700__ $$aBalza, N.
000148538 700__ $$aVillagrasa, R.A.
000148538 700__ $$aVázquez,J. F.
000148538 700__ $$aGonzález-Timoneda, Y.A.
000148538 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000148538 7102_ $$14009$$2740$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Social
000148538 773__ $$g38, 4 (2014), 346-353$$pCancer Epidemiology$$tCancer Epidemiology$$x1877-7821
000148538 8564_ $$s362266$$uhttps://zaguan.unizar.es/record/148538/files/texto_completo.pdf$$yPostprint
000148538 8564_ $$s2435418$$uhttps://zaguan.unizar.es/record/148538/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000148538 909CO $$ooai:zaguan.unizar.es:148538$$particulos$$pdriver
000148538 951__ $$a2025-01-20-14:52:37
000148538 980__ $$aARTICLE